Gene Symbol | GBP2 |
---|---|
Entrez Gene | 2634 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | guanylate binding protein 2, interferon-inducible |
Other Description | GTP-binding protein 2|guanine nucleotide-binding protein 2|interferon-induced guanylate-binding protein 2 |
Swissprots | Q6GPH0 P32456 Q6IAU2 Q86TB0 |
Accessions | EAW73146 P32456 AI085798 AI400402 AI445567 AK002150 AK057968 AK122866 AK226018 AK314325 BAG36973 BC022272 AAH22272 BC073163 AAH73163 BM993865 CA390345 CR457062 CAG33343 DB229415 DB274428 M55543 AAA67323 NM_004120 NP_004111 |
Function | Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm. Nucleus. Golgi apparatus membrane; Lipid-anchor. |