Gene Symbol | GBP2 |
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Entrez Gene | 2634 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | guanylate binding protein 2, interferon-inducible |
Other Description | GTP-binding protein 2|guanine nucleotide-binding protein 2|interferon-induced guanylate-binding protein 2 |
Swissprots | Q6GPH0 P32456 Q6IAU2 Q86TB0 |
Accessions | EAW73146 P32456 AI085798 AI400402 AI445567 AK002150 AK057968 AK122866 AK226018 AK314325 BAG36973 BC022272 AAH22272 BC073163 AAH73163 BM993865 CA390345 CR457062 CAG33343 DB229415 DB274428 M55543 AAA67323 NM_004120 NP_004111 |
Function | Hydrolyzes GTP to GMP in two consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm. Nucleus. Golgi apparatus membrane; Lipid-anchor. |
GBP2 CRISPR/Cas9 KO Plasmid (h) - sc-402140 from Santa Cruz Biotechnology
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GBP2 HDR Plasmid (h) - sc-402140-HDR from Santa Cruz Biotechnology
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GBP2 Double Nickase Plasmid (h) - sc-402140-NIC from Santa Cruz Biotechnology
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GBP2 Double Nickase Plasmid (h2) - sc-402140-NIC-2 from Santa Cruz Biotechnology
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GBP2 CRISPR Activation Plasmid (h) - sc-402140-ACT from Santa Cruz Biotechnology
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GBP2 CRISPR Activation Plasmid (h2) - sc-402140-ACT-2 from Santa Cruz Biotechnology
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GBP2 Lentiviral Activation Particles (h) - sc-402140-LAC from Santa Cruz Biotechnology
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GBP2 Lentiviral Activation Particles (h2) - sc-402140-LAC-2 from Santa Cruz Biotechnology
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GBP2 siRNA (h) - sc-106877 from Santa Cruz Biotechnology
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GBP2 shRNA Plasmid (h) - sc-106877-SH from Santa Cruz Biotechnology
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GBP2 shRNA (h) Lentiviral Particles - sc-106877-V from Santa Cruz Biotechnology
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GBP2 RNAi - H00002634-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN9169 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9169 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05446 from Sigma-Aldrich
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GBP2 siRNA (Human) - CRH1749 from Cohesion Biosciences
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GBP2 - MBS8239340 from MyBioSource
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shRNA set against Human GBP2 (NM_004120.3) - SHH299802 from Creative biogene
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shRNA set against Human GBP2(NM_004120.3) - SHH078977 from Creative biogene
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GBP2 shRNA Plasmid (Human) - CHH1749 from Cohesion Biosciences
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GBP2 miRNA 3'UTR clone - MiUTR1H-03973 from Creative biogene
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