Gene Symbol |
NUP210
|
Entrez Gene |
23225
|
Alt Symbol |
GP210, POM210
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
nucleoporin 210kDa
|
Other Description |
nuclear envelope pore membrane protein POM 210|nuclear pore membrane glycoprotein 210|nuclear pore protein gp210|nucleoporin Nup210|pore membrane protein of 210 kDa
|
Swissprots |
Q8TEM1 Q6NXG6 Q9UFP3 Q8NBJ1 A6NN56 Q9H6C8 O94980
|
Accessions |
EAW64150 EAW64151 EAW64152 EAW64153 EAW64154 Q8TEM1 AA909765 AB020713 BAA74929 AK026042 BAB15332 AK074101 BAB84927 AK075545 BAC11688 AK225409 AL117527 CAB55979 BC020573 BC067089 AAH67089 BC068109 BM508095 HY177936 XM_005264994 XP_005265051 XM_011533538 XP_011531840 XM_011533539 XP_011531841 NM_024923 NP_079199
|
Function |
Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity. {ECO:0000269|PubMed:14517331}.
|
Subcellular Location |
Nucleus, nuclear pore complex {ECO:0000269|PubMed:2195063}. Nucleus membrane {ECO:0000269|PubMed:2195063}; Single-pass type I membrane protein {ECO:0000269|PubMed:2195063}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:2195063}; Single-pass type I membrane protein {ECO:0000269|PubMed:2195063}.
|
Tissue Specificity |
Ubiquitous expression, with highest levels in lung, liver, pancreas, testis, and ovary, intermediate levels in brain, kidney, and spleen, and lowest levels in heart and skeletal muscle. {ECO:0000269|PubMed:10048485}.
|
Top Pathways |
RNA transport
|