Gene Symbol | NUP210 |
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Entrez Gene | 23225 |
Alt Symbol | GP210, POM210 |
Species | Human |
Gene Type | protein-coding |
Description | nucleoporin 210kDa |
Other Description | nuclear envelope pore membrane protein POM 210|nuclear pore membrane glycoprotein 210|nuclear pore protein gp210|nucleoporin Nup210|pore membrane protein of 210 kDa |
Swissprots | Q8TEM1 Q6NXG6 Q9UFP3 Q8NBJ1 A6NN56 Q9H6C8 O94980 |
Accessions | EAW64150 EAW64151 EAW64152 EAW64153 EAW64154 Q8TEM1 AA909765 AB020713 BAA74929 AK026042 BAB15332 AK074101 BAB84927 AK075545 BAC11688 AK225409 AL117527 CAB55979 BC020573 BC067089 AAH67089 BC068109 BM508095 HY177936 XM_005264994 XP_005265051 XM_011533538 XP_011531840 XM_011533539 XP_011531841 NM_024923 NP_079199 |
Function | Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity. {ECO:0000269|PubMed:14517331}. |
Subcellular Location | Nucleus, nuclear pore complex {ECO:0000269|PubMed:2195063}. Nucleus membrane {ECO:0000269|PubMed:2195063}; Single-pass type I membrane protein {ECO:0000269|PubMed:2195063}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:2195063}; Single-pass type I membrane protein {ECO:0000269|PubMed:2195063}. |
Tissue Specificity | Ubiquitous expression, with highest levels in lung, liver, pancreas, testis, and ovary, intermediate levels in brain, kidney, and spleen, and lowest levels in heart and skeletal muscle. {ECO:0000269|PubMed:10048485}. |
Top Pathways | RNA transport |
gp210 CRISPR/Cas9 KO Plasmid (h) - sc-409439 from Santa Cruz Biotechnology
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gp210 HDR Plasmid (h) - sc-409439-HDR from Santa Cruz Biotechnology
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gp210 Double Nickase Plasmid (h) - sc-409439-NIC from Santa Cruz Biotechnology
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gp210 Double Nickase Plasmid (h2) - sc-409439-NIC-2 from Santa Cruz Biotechnology
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gp210 CRISPR Activation Plasmid (h) - sc-409439-ACT from Santa Cruz Biotechnology
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gp210 CRISPR Activation Plasmid (h2) - sc-409439-ACT-2 from Santa Cruz Biotechnology
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gp210 Lentiviral Activation Particles (h) - sc-409439-LAC from Santa Cruz Biotechnology
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gp210 Lentiviral Activation Particles (h2) - sc-409439-LAC-2 from Santa Cruz Biotechnology
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gp210 siRNA (h) - sc-75164 from Santa Cruz Biotechnology
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gp210 shRNA Plasmid (h) - sc-75164-SH from Santa Cruz Biotechnology
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gp210 shRNA (h) Lentiviral Particles - sc-75164-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU011511 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15624 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15624 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09680 from Sigma-Aldrich
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NUP210 siRNA (Human) - CRH8102 from Cohesion Biosciences
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shRNA set against Human NUP210 (NM_024923.2) - SHH356424 from Creative biogene
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Human NUP210 siRNA - orb268604 from Biorbyt
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NUP210 shRNA Plasmid (Human) - CHH8102 from Cohesion Biosciences
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NUP210 miRNA 3'UTR clone - MiUTR1H-06989 from Creative biogene
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