Gene Symbol | ATP2B1 |
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Entrez Gene | 490 |
Alt Symbol | PMCA1, PMCA1kb |
Species | Human |
Gene Type | protein-coding |
Description | ATPase, Ca++ transporting, plasma membrane 1 |
Other Description | plasma membrane calcium pump|plasma membrane calcium-transporting ATPase 1 |
Swissprots | Q16504 Q13819 Q12992 Q93082 Q12993 Q13820 Q13821 P20020 |
Accessions | AAA58381 AAA58382 AAA58383 AAD09924 AAD09925 EAW97429 EAW97430 EAW97431 EAW97432 EAW97433 EAW97434 P20020 AB208896 BAD92133 AF070606 AK024895 AK027053 AK308723 AY740526 AAV41065 BC015346 AAH15346 BM974301 DQ201776 ABG24240 J04027 AAA74511 M95541 AAA35999 M95542 AAA36000 S49852 AAB24324 U15686 AAA60983 U15687 AAA60984 XM_005268919 XP_005268976 XM_011538407 XP_011536709 XM_011538408 XP_011536710 XM_011538409 XP_011536711 XM_011538410 XP_011536712 XM_011538411 XP_011536713 XM_011538412 XP_011536714 XR_944556 NM_001001323 NP_001001323 NM_001682 NP_001673 |
Function | This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Isoform B is ubiquitously expressed. Isoform C is found in brain cortex, skeletal muscle and heart muscle. Isoform D has only been found in fetal skeletal muscle. Isoform K has been found in small intestine and liver. |
Top Pathways | Calcium signaling pathway, Salivary secretion, Pancreatic secretion, Mineral absorption, Endocrine and other factor-regulated calcium reabsorption |
PMCA1 CRISPR/Cas9 KO Plasmid (h) - sc-402691 from Santa Cruz Biotechnology
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PMCA1 HDR Plasmid (h) - sc-402691-HDR from Santa Cruz Biotechnology
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PMCA1 Double Nickase Plasmid (h) - sc-402691-NIC from Santa Cruz Biotechnology
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PMCA1 Double Nickase Plasmid (h2) - sc-402691-NIC-2 from Santa Cruz Biotechnology
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PMCA1 CRISPR Activation Plasmid (h) - sc-402691-ACT from Santa Cruz Biotechnology
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PMCA1 CRISPR Activation Plasmid (h2) - sc-402691-ACT-2 from Santa Cruz Biotechnology
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PMCA1 Lentiviral Activation Particles (h) - sc-402691-LAC from Santa Cruz Biotechnology
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PMCA1 Lentiviral Activation Particles (h2) - sc-402691-LAC-2 from Santa Cruz Biotechnology
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PMCA1 siRNA (h) - sc-42596 from Santa Cruz Biotechnology
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PMCA1 shRNA Plasmid (h) - sc-42596-SH from Santa Cruz Biotechnology
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PMCA1 shRNA (h) Lentiviral Particles - sc-42596-V from Santa Cruz Biotechnology
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PMCA1 RNAi - H00000490-R04 from Novus Biologicals
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PMCA1 RNAi - H00000490-R03 from Novus Biologicals
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MISSION® esiRNA - EHU141451 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3689 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3689 from Sigma-Aldrich
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ATP2B1 siRNA (Human) - CRH0344 from Cohesion Biosciences
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ATP2B1 - MBS8240130 from MyBioSource
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shRNA set against Human ATP2B1 (NM_001682.2) - SHH242638 from Creative biogene
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shRNA set against Human ATP2B1(NM_001682.2) - SHG081605 from Creative biogene
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shRNA set against Human ATP2B1(NM_001001323.1) - SHG081863 from Creative biogene
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shRNA set against Human ATP2B1(NM_001682.2) - SHG081913 from Creative biogene
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Human ATP2B1 siRNA - orb260846 from Biorbyt
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ATP2B1 shRNA Plasmid (Human) - CHH0344 from Cohesion Biosciences
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ATP2B1 miRNA 3'UTR clone - MiUTR1H-00684 from Creative biogene
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