| Gene Symbol |
B3GALT1
|
| Entrez Gene |
8708
|
| Alt Symbol |
beta3Gal-T1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
|
| Other Description |
UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1|beta-1,3-GalTase 1|beta-1,3-galactosyltransferase 1|beta-3-galt1|beta3GalT1
|
| Swissprots |
D3DPB8 Q9Y5Z6 Q53SS2
|
| Accessions |
AAY15002 BAA94492 EAX11306 EAX11307 Q9Y5Z6 AF117222 AAD23451 BC101545 AAI01546 BC104813 AAI04814 E07739 HG494816 XM_005246931 XP_005246988 XM_006712819 XP_006712882 XM_011512084 XP_011510386 XM_011512085 XP_011510387 NM_020981 NP_066191
|
| Function |
Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-N- acetylglucosamine (beta-GlcNAc) residue. Involved in the biosynthesis of the carbohydrate moieties of glycolipids and glycoproteins. Inactive towards substrates with terminal alpha-N- acetylglucosamine (alpha-GlcNAc) or alpha-N-acetylgalactosamine (alpha-GalNAc) residues. {ECO:0000269|PubMed:9582303}.
|
| Subcellular Location |
Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Detected in brain and colon mucosa and to a lesser extent in colon adenocarcinoma cells. {ECO:0000269|PubMed:10356986, ECO:0000269|PubMed:9582303}.
|
| Top Pathways |
Glycosphingolipid biosynthesis - lacto and neolacto series
|
![Western Blot: B3GALT1 Overexpression Lysate (Adult Normal) [NBL1-07876] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for B3GALT1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7006_B3GALT1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-07876-img0002.jpg)