| Gene Symbol |
SRF
|
| Entrez Gene |
6722
|
| Alt Symbol |
MCM1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
serum response factor (c-fos serum response element-binding transcription factor)
|
| Other Description |
serum response factor
|
| Swissprots |
P11831 Q5T648
|
| Accessions |
CAM91173 EAX04161 EAX04162 P11831 AB209128 BAD92365 AI085561 AK300467 BAG62186 BC048211 AAH48211 BC052572 AAH52572 J03161 AAA36647 NM_001292001 NP_001278930 NM_003131 NP_003122
|
| Function |
SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Required for cardiac differentiation and maturation.
|
| Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00251, ECO:0000269|PubMed:19350017}.
|
| Top Pathways |
MAPK signaling pathway, HTLV-I infection, Viral carcinogenesis, cGMP-PKG signaling pathway
|
![Western Blot: Serum Response Factor SRF Overexpression Lysate (Adult Normal) [NBP2-10873] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Serum Response Factor SRF.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/10425_Serum%2520Response%2520Factor%2520SRF%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10873-img0001.jpg)