Gene Symbol | RPS6KB2 |
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Entrez Gene | 6199 |
Alt Symbol | KLS, P70-beta, P70-beta-1, P70-beta-2, S6K-beta2, S6K2, SRK, STK14B, p70(S6K)-beta, p70S6Kb |
Species | Human |
Gene Type | protein-coding |
Description | ribosomal protein S6 kinase, 70kDa, polypeptide 2 |
Other Description | 70 kDa ribosomal protein S6 kinase 2|P70S6K2|S6 kinase-related kinase|S6K-beta|S6K-beta-2|p70 S6 kinase beta|p70 S6K-beta|p70 S6KB|p70 ribosomal S6 kinase beta|p70-S6K 2|ribosomal protein S6 kinase beta-2|serine/threonine-protein kinase 14 beta|serine/threonine-protein kinase 14B |
Swissprots | B2RMZ9 Q9UEC1 B4DML8 O94809 Q9UBS0 |
Accessions | EAW74618 EAW74619 EAW74620 EAW74621 Q9UBS0 AB016869 BAA34402 AB019245 BAA37145 AB208827 BAD92064 AF076931 AAD46063 AF099739 AAD20990 AK297527 BAG59930 BC000094 AAH00094 BC006106 AAH06106 BC136564 AAI36565 BX337895 BX538119 XM_005274164 XP_005274221 XM_005274165 XP_005274222 XM_006718655 XP_006718718 XM_006718656 XP_006718719 XM_006718657 XP_006718720 XR_247207 XR_247208 NM_003952 NP_003943 NM_001007071 |
Function | Phosphorylates specifically ribosomal protein S6. |
Subcellular Location | Cytoplasm. Nucleus. |
Top Pathways | Fc gamma R-mediated phagocytosis, Proteoglycans in cancer, Choline metabolism in cancer, AMPK signaling pathway, PI3K-Akt signaling pathway |
p70 S6 kinase β siRNA (h) - sc-39209 from Santa Cruz Biotechnology
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p70 S6 kinase β shRNA Plasmid (h) - sc-39209-SH from Santa Cruz Biotechnology
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p70 S6 kinase β shRNA (h) Lentiviral Particles - sc-39209-V from Santa Cruz Biotechnology
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p70 S6 Kinase beta/S6K2 RNAi - H00006199-R03 from Novus Biologicals
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p70 S6 Kinase beta/S6K2 RNAi - H00006199-R04 from Novus Biologicals
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MISSION® esiRNA - EHU003481 from Sigma-Aldrich
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MISSION® siRNA - SIHK2026 from Sigma-Aldrich
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MISSION® siRNA - SIHK2025 from Sigma-Aldrich
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MISSION® siRNA - SIHK2029 from Sigma-Aldrich
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MISSION® siRNA - SIHK2027 from Sigma-Aldrich
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MISSION® siRNA - SIHK2028 from Sigma-Aldrich
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MISSION® siRNA - SIHK2030 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1305 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1305 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01424 from Sigma-Aldrich
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RPS6KB2 siRNA (Human) - CRH4174 from Cohesion Biosciences
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RPS6KB2 - MBS8241230 from MyBioSource
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shRNA set against Human RPS6KB2 (NM_003952.2) - SHH399620 from Creative biogene
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shRNA set against Human RPS6KB2(NM_003952.2) - SHR198084 from Creative biogene
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Human RPS6KB2 siRNA - orb264676 from Biorbyt
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RPS6KB2 shRNA Plasmid (Human) - CHH4174 from Cohesion Biosciences
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RPS6KB2 miRNA 3'UTR clone - MiUTR1H-09034 from Creative biogene
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