EPC1

Gene Symbol EPC1
Entrez Gene 80314
Alt Symbol Epl1
Species Human
Gene Type protein-coding
Description enhancer of polycomb homolog 1 (Drosophila)
Other Description enhancer of polycomb homolog 1
Swissprots Q5VW54 Q9H7T7 Q96RR6 Q96LF4 Q8NE21 Q5VW56 Q5VW58 B4DSC3 D3DRX7 Q9H2F5 Q8NAQ4
Accessions EAW85972 EAW85973 EAW85974 EAW85975 Q9H2F5 AA553969 AF277374 AAG41402 AF286905 AAK60501 AK024329 BAB14888 AK092304 BAC03857 AK299676 BAG61585 AK309309 AK309822 AW021213 BC036529 AAH36529 BG719217 BI029680 BI461563 BM717660 BQ007483 BU195035 BX476993 CB159405 CN370473 CR749375 CAH18228 D60263 DA333251 DB070690 DB447845 XM_006717510 XP_006717573 XM_011519712 XP_011518014 XR_428649 NM_001272004 NP_001258933 NM_001272019 NP_001258948 NM_001282391 NP_001269320 NM_025209 NP_079485 NR_104159 NR_104160
Function Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. {ECO:0000269|PubMed:14966270}.
Subcellular Location Nucleus {ECO:0000269|PubMed:10976108}.

EPC1 (D-6) - sc-373840 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
EPC1 (D-6): sc-373840. Western blot analysis of EPC1 expression in non-transfected (A) and human EPC1 transfected (B) whole cell lysates.

EPC1 (C-20) - sc-48152 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

EPC1 (H-103) - sc-134532 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
EPC1 (H-103): sc-134532. Western blot analysis of EPC1 expression in HeLa (A) and RAW 264.7 (B) whole cell lysates.

EPC1 (C-15) - sc-48151 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

EPC1 (N-15) - sc-48154 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
EPC1 (N-15): sc-48154. Western blot analysis of EPC1 expression in HeLa nuclear extract.

Anti-EPC1 antibody - ab5514 from Abcam

Prices $380.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Specificity of ab5514 against EPC1A and B: Detection using indirest immunofluorescence of the signal corresponding to EPC1 in EPC1 in 293 Cells were fixed using 4% formaldehyde blocked with PBS containing 3% milk and 0.5% Triton x-100 (sigma) incubated for 1 hour at 37 C with ab5514 at a 1/50 dilution. The cells were then washed three times and incubated for 1 hour at 37 C with a donkey anti-rabbit antibody coupled with Alexa Fluor 488 (Molecular probes) at a 1/500 dilution, washed three times, stained with DAPI and mounted with Vectasheild(Abcyss). A: Acquisition on a CCD camera B: Confocal microscopy (3um stack along Z axis). C.

Anti-EPC1 antibody - ab112043 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-EPC1 antibody (ab112043) at 0.1 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µgdeveloped using the ECL technique

Anti-EPC1 antibody - ab192518 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-EPC1 antibody - ab168996 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-EPC1 antibody (ab168996) at 1/500 dilutionLane 1 : EPC1 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.

Anti-EPC1 Antibody (aa695-799) - LS-C307937 from LifeSpan Bioscience

Prices $455.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal

Anti-EPC1 Antibody - LS-C341880 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-EPC1 Antibody - LS-C346097 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence blot of HeLa cell using EPC1 antibody. Blue: DAPI for nuclear staining.

Anti-EPC1 Antibody (aa325-375) - LS-C289811 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human EPC1 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-EPC1 antibody used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 6 ug/mg lysate. EPC1 was also immunoprecipitated by rabbit anti-EPC1 antibody BL11146, which recognizes a downstream epitope. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 10 seconds (B).

Anti-EPC1 Antibody (aa305-334) - LS-C203965 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
EPC1 Antibody western blot of A2058,HeLa cell line and mouse heart tissue lysates (35 ug/lane). The EPC1 antibody detected the EPC1 protein (arrow).

Anti-EPC1 Antibody (aa323-372) IHC-plus™ - LS-B9739 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-EPC1 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9739 concentration 20 ug/ml.

EPC1 Antibody - NBP1-71865 from Novus Biologicals

Prices $369.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: EPC1 Antibody [NBP1-71865] - Whole cell lysate (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. Affinity purified rabbit anti-EPC1 antibody used for WB at 0.1 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 6 mcg/mg lysate. EPC1 was also immunoprecipitated by another rabbit anti-EPC1 antibody.,

EPC1 Antibody - H00080314-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: EPC1 Antibody [H00080314-A01] - EPC1 polyclonal antibody (A01), Lot # ABNOVA060706QCS1 Western Blot analysis of EPC1 expression in Hela NE ( Cat # L013V3 ).

EPC1 Antibody - H00080314-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: EPC1 Antibody [H00080314-B01] - analysis of EPC1 expression in transfected 293T cell line by EPC1 MaxPab polyclonal antibody (B01). Lane 1: EPC1 transfected lysate (90.90 KDa). Lane 2: Non-transfected lysate.

EPC1 Antibody (4F7) - H00080314-M01A from Novus Biologicals

Prices $349.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 4F7

Anti-EPC1 antibody produced in rabbit - SAB2100688 from Sigma-Aldrich

Prices $347.50
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-EPC1: <B>Cat. No.SAB2100688</B>: EPC1 in HepG2 cell lysate with EPC1 antibody at 1.0 μg/mL.

ANTI-EPC1 (CENTER) antibody produced in rabbit - SAB1306753 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-EPC1 (Center): <B>Cat. No. SAB1306753</B>: EPC1 Antibody (Center) western blot analysis in A2058,HeLa cell line and Mouse heart tissue lysates (35 μg/lane).

EPC1 antibody - middle region (ARP33343_P050) - ARP33343_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

EPC1-Antibody-Center - AP20494c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
EPC1 Antibody (Center) (Cat. #AP20494c) western blot analysis in A2058,Hela cell line and mouse heart tissue lysates (35ug/lane).This demonstrates the EPC1 antibody detected the EPC1 protein (arrow).

EPC1 antibody - GTX99644 from GeneTex

Prices $239.00
Sizes 50 μl
Host Mouse
Clonality Polyclonal

EPC1 Antibody - middle region (OAAB18017) - OAAB18017 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
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