| Gene Symbol |
EPC1
|
| Entrez Gene |
80314
|
| Alt Symbol |
Epl1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
enhancer of polycomb homolog 1 (Drosophila)
|
| Other Description |
enhancer of polycomb homolog 1
|
| Swissprots |
Q5VW54 Q9H7T7 Q96RR6 Q96LF4 Q8NE21 Q5VW56 Q5VW58 B4DSC3 D3DRX7 Q9H2F5 Q8NAQ4
|
| Accessions |
EAW85972 EAW85973 EAW85974 EAW85975 Q9H2F5 AA553969 AF277374 AAG41402 AF286905 AAK60501 AK024329 BAB14888 AK092304 BAC03857 AK299676 BAG61585 AK309309 AK309822 AW021213 BC036529 AAH36529 BG719217 BI029680 BI461563 BM717660 BQ007483 BU195035 BX476993 CB159405 CN370473 CR749375 CAH18228 D60263 DA333251 DB070690 DB447845 XM_006717510 XP_006717573 XM_011519712 XP_011518014 XR_428649 NM_001272004 NP_001258933 NM_001272019 NP_001258948 NM_001282391 NP_001269320 NM_025209 NP_079485 NR_104159 NR_104160
|
| Function |
Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. {ECO:0000269|PubMed:14966270}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:10976108}.
|
