CYSLTR2

Gene Symbol CYSLTR2
Entrez Gene 57105
Alt Symbol CYSLT2, CYSLT2R, HG57, HPN321, KPG_011, PSEC0146, hGPCR21
Species Human
Gene Type protein-coding
Description cysteinyl leukotriene receptor 2
Other Description G protein-coupled receptor|G-protein coupled receptor GPCR21|G-protein coupled receptor HG57|cysteinyl leukotriene CysLT2 receptor
Swissprots Q9NS75 Q9HCQ2
Accessions AAG17281 AAK69485 AAQ91330 BAB16379 BAB89316 CAC69300 CAC69324 CAD19004 CAD20523 CAD35281 CAD68128 CAJ58194 EAX08802 Q9NS75 AB038269 BAB03601 AB041947 BAD83598 AK291739 BAF84428 AY853711 AAW47925 BC069160 AAH69160 BC096832 AAH96832 EF141523 ABO61874 EF141524 ABO61875 EF141525 ABO61876 EF141526 ABO61877 EF141527 ABO61878 EF141528 ABO61879 EF141529 ABO61880 EF141530 ABO61881 NM_001308465 NP_001295394 NM_001308467 NP_001295396 NM_001308468 NP_001295397 NM_001308469 NP_001295398 NM_001308470 NP_001295399 NM_001308471 NP_001295400 NM_001308476 NP_001295405 NM_020377 NP_065110
Function Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol- calcium second messenger system. Stimulation by BAY u9773, a partial agonist, induces specific contractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascular endothelium. The rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Widely expressed, with highest levels in the heart, placenta, spleen, peripheral blood leukocytes and adrenal gland. In lung, expressed in the interstitial macrophages, and slightly in smooth muscle cells.
Top Pathways Calcium signaling pathway, Neuroactive ligand-receptor interaction

CysLT 2 Receptor (E-20) - sc-27097 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CysLT<sub>2</sub> Receptor (E-20): sc-27097. Immunoperoxidase staining of formalin fixed, paraffin-embedded human placenta tissue showing cytoplasmic and membrane staining of trophoblastic cells and decidual cells.

CysLT 2 Receptor (F-15) - sc-27096 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CysLT<sub>2</sub> Receptor (F-15): sc-27096. Western blot analysis of CysLT<sub>2</sub> Receptor expression in HeLa (A) and JAR (B) whole cell lysates.

CysLT 2 Receptor (K-14) - sc-27914 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CysLT<sub>2</sub> Receptor (K-14): sc-27914. Western blot analysis of CysLT<sub>2</sub> Receptor expression in HeLa (A) and JAR (B) whole cell lysates.

CysLT 2 Receptor (V-15) - sc-27915 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CysLT<sub>2</sub> Receptor (V-15): sc-27915. Western blot analysis of CysLT<sub>2</sub> Receptor expression in HeLa (A) and JAR (B) whole cell lysates.

Anti-CysLT2 antibody - ab75160 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CysLT2 antibody (ab75160) at 1/500 dilutionLane 1 : Extracts from HeLa cellsLane 2 : Extracts from COLO cellsLane 3 : Extracts from HeLa cells with immunising peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-CysLT2 antibody - ab93484 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CysLT2 antibody (ab93484) at 1/2000 dilutionLane 1 : SGC cell lysate at 32 µgLane 2 : THP1 cell lysate at 52 µgLane 3 : IM-9 cell lysate at 28 µg

Anti-CysLT2 antibody - ab136035 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-CysLT2 antibody (ab136035) at 1/500 dilution + HT29 cell lysate at 30 µg

Anti-CysLT2 antibody - ab115453 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab115453, at 10 µg/ml, staining CysLT2 in formalin-fixed, paraffin-embedded Human Heart tissue by Immunohistochemistry, using a biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-CysLT2 antibody - C-terminal - ab188749 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of Human spleen tissue labeling CysLT2 using ab188749 at 5 μg/ml.

Anti-CYSLT2 / CYSLTR2 Antibody - LS-C137446 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYSLT2 / CYSLTR2 Antibody - LS-C146666 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYSLT2 / CYSLTR2 Antibody (aa281-330) - LS-C120640 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of extracts from HeLa/COLO cells, using CLTR2 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-CYSLT2 / CYSLTR2 Antibody (aa281-330) - LS-C120570 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of extracts from COLO cells, using CYSLTR2 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-CYSLT2 / CYSLTR2 Antibody (aa275-324) - LS-C291849 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYSLT2 / CYSLTR2 Antibody (Lys322) - LS-C177097 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of CysLTR2 (K322) pAb in extracts from HeLa cells.

Anti-CYSLT2 / CYSLTR2 Antibody IHC-plus™ - LS-B7897 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Anti-CYSLT2 / CYSLTR2 antibody IHC of human liver, Kupffer cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7897 dilution 5 ug/ml.

Anti-CYSLT2 / CYSLTR2 Antibody (His324) - LS-C177184 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of CysLTR2 (H324) pAb in extracts from COLO cells.

Anti-CYSLT2 / CYSLTR2 Antibody (C-Terminus) IHC-plus™ - LS-A2264 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Anti-CYSLTR2 / CYSLT2 antibody LS-A2264 IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-CYSLT2 / CYSLTR2 Antibody (Extracellular Domain) IHC-plus™ - LS-A2255 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Anti-CYSLTR2 / CYSLT2 antibody LS-A2255 IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-CYSLT2 / CYSLTR2 Antibody (Extracellular Domain) IHC-plus™ - LS-A3305 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Anti-CYSLTR2 / CYSLT2 antibody LS-A3305 IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-CYSLT2 / CYSLTR2 Antibody (C-Terminus) IHC-plus™ - LS-A473 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Anti-CYSLTR2 / CYSLT2 antibody LS-A473 IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-CYSLT2 / CYSLTR2 Antibody (N-Terminus) IHC-plus™ - LS-A512 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Anti-CYSLTR2 / CYSLT2 antibody LS-A512 IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Cysteinyl Leukotriene R2/CysLTR2 Antibody - NLS3305 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: Cysteinyl Leukotriene R2/CysLTR2 Antibody [NLS3305] - IHC staining of human heart.

Cysteinyl Leukotriene R2/CysLTR2 Antibody - NBP1-00778 from Novus Biologicals

Host Rabbit
Clonality Polyclonal
Western Blot: CysLTR2 Antibody [NBP1-00778] - Western blot (WB) analysis of CysLTR2 (K322) antibody in extracts from HeLa cells

Cysteinyl Leukotriene R2/CysLTR2 Antibody - NBP1-00777 from Novus Biologicals

Host Rabbit
Clonality Polyclonal
Western Blot: CysLT2 Antibody [NBP1-00777] - Western blot (WB) analysis of CysLT2 (H324) antibody in extracts from COLO cells.
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