| Gene Symbol |
MRGPRX4
|
| Entrez Gene |
117196
|
| Alt Symbol |
GPCR, MRGX4, SNSR6
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
MAS-related GPR, member X4
|
| Other Description |
G protein-coupled receptor MRGX4|G protein-coupled receptor SNSR5|G protein-coupled receptor SNSR6|mas-related G-protein coupled receptor member X4|sensory neuron-specific G-protein coupled receptor 5/6
|
| Swissprots |
Q3KNU3 Q3KNU4 Q96LA9 Q8TDD6 Q8TDD7 Q502W0
|
| Accessions |
AAK91807 AAL86882 AAL86883 EAW68416 Q96LA9 BC095509 AAH95509 BC107099 AAI07100 BC107100 AAI07101 CN835944 NM_054032 NP_473373
|
| Function |
Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons. {ECO:0000269|PubMed:11850634}.
|