Gene Symbol | MRGPRX4 |
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Entrez Gene | 117196 |
Alt Symbol | GPCR, MRGX4, SNSR6 |
Species | Human |
Gene Type | protein-coding |
Description | MAS-related GPR, member X4 |
Other Description | G protein-coupled receptor MRGX4|G protein-coupled receptor SNSR5|G protein-coupled receptor SNSR6|mas-related G-protein coupled receptor member X4|sensory neuron-specific G-protein coupled receptor 5/6 |
Swissprots | Q3KNU3 Q3KNU4 Q96LA9 Q8TDD6 Q8TDD7 Q502W0 |
Accessions | AAK91807 AAL86882 AAL86883 EAW68416 Q96LA9 BC095509 AAH95509 BC107099 AAI07100 BC107100 AAI07101 CN835944 NM_054032 NP_473373 |
Function | Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons. {ECO:0000269|PubMed:11850634}. |
MRGX4 CRISPR/Cas9 KO Plasmid (h) - sc-414109 from Santa Cruz Biotechnology
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MRGX4 HDR Plasmid (h) - sc-414109-HDR from Santa Cruz Biotechnology
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MRGX4 Double Nickase Plasmid (h) - sc-414109-NIC from Santa Cruz Biotechnology
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MRGX4 Double Nickase Plasmid (h2) - sc-414109-NIC-2 from Santa Cruz Biotechnology
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MRGX4 CRISPR Activation Plasmid (h) - sc-414109-ACT from Santa Cruz Biotechnology
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MRGX4 CRISPR Activation Plasmid (h2) - sc-414109-ACT-2 from Santa Cruz Biotechnology
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MRGX4 Lentiviral Activation Particles (h) - sc-414109-LAC from Santa Cruz Biotechnology
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MRGX4 Lentiviral Activation Particles (h2) - sc-414109-LAC-2 from Santa Cruz Biotechnology
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MRGX4 siRNA (h) - sc-106241 from Santa Cruz Biotechnology
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MRGX4 shRNA Plasmid (h) - sc-106241-SH from Santa Cruz Biotechnology
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MRGX4 shRNA (h) Lentiviral Particles - sc-106241-V from Santa Cruz Biotechnology
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MRGX4 RNAi - H00117196-R02 from Novus Biologicals
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MISSION® esiRNA - EHU109541 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14539 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14539 from Sigma-Aldrich
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MRGPRX4 siRNA (Human) - CRJ4561 from Cohesion Biosciences
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shRNA set against Human MRGPRX4 (NM_054032.3) - SHH344444 from Creative biogene
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Human MRGPRX4 siRNA - orb275062 from Biorbyt
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MRGPRX4 shRNA Plasmid (Human) - CHJ4561 from Cohesion Biosciences
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MRGPRX4 miRNA 3'UTR clone - MiUTR4H-TG05624 from Creative biogene
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