Trpm2

Gene Symbol Trpm2
Entrez Gene 28240
Alt Symbol 9830168K16Rik, C79133, LTRPC2, TRPC7, Trp7, Trrp7
Species Mouse
Gene Type protein-coding
Description transient receptor potential cation channel, subfamily M, member 2
Other Description LTrpC-2|long transient receptor potential channel 2|transient receptor potential cation channel subfamily M member 2|transient receptor potential channel 7|transient receptor protein 7
Swissprots Q91YD4
Accessions EDL31767 EDL31768 Q91YD4 AB166747 BAD83707 AJ344343 CAC69081 AJ878415 CAI47592 AK034099 AK036731 AK039405 AK134735 BAE22263 AK136905 BC118920 BC141391 AAI41392 CJ108999 XM_006513729 XP_006513792 XM_006513730 XP_006513793 XM_006513731 XP_006513794 XM_006513732 XP_006513795 XM_006513733 XP_006513796 XM_011243470 XP_011241772 XR_871714 NM_138301 NP_612174
Function Nonselective, voltage-independent cation channel mediating sodium and calcium ion influx in response to oxidative stress. Extracellular calcium passes through the channel and acts from the intracellular side as a positive regulator in channel activation. Activated by ADP-ribose, nicotinamide adenine dinucleotide (NAD(+)), reactive nitrogen species and arachidonic acid. Inactivated by intracellular ATP. Confers susceptibility to cell death following oxidative stress. Has ADP-ribose pyrophosphatase activity (By similarity). {ECO:0000250}.
Subcellular Location Membrane {ECO:0000269|PubMed:11804595}; Multi-pass membrane protein {ECO:0000269|PubMed:11804595}.
Tissue Specificity Widely expressed, with highest levels in lung, spleen, eye and brain. {ECO:0000269|PubMed:11804595}.
Top Pathways Oxytocin signaling pathway

TRPM2 Antibody - NB110-81601 from Novus Biologicals

Prices $99.00, $299.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: TRPM2 Antibody [NB110-81601] - Lane 1: CHO cells untransfected. Lane 2: CHO cell transfected with rat TRPM2 Lane 3: Mouse cortical neurons (cultured) Photo courtesy of Dr. Paco Herson, Oregon Health & Science University.

TRPM2 Antibody - NB110-82364 from Novus Biologicals

Prices $99.00, $279.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: TRPM2 Antibody [NB110-82364] - Detection of TRPM2 in mouse brain membrane lysates using NB110-82364.

TRPM2 Antibody [Alexa Fluor (R) 700] - NB110-81601AF700 from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rabbit
Clonality Polyclonal

TRPM2 Antibody [Alexa Fluor (R) 647] - NB110-81601AF647 from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rabbit
Clonality Polyclonal

TRPM2 Antibody [Alexa Fluor (R) 488] - NB110-81601AF488 from Novus Biologicals

Prices $329.00
Sizes 100 tests
Host Rabbit
Clonality Polyclonal

TRPM2 Antibody [Alexa Fluor (R) 405] - NB110-81601AF405 from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rabbit
Clonality Polyclonal

TRPM2 Antibody [FITC] - NB110-81601F from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TRPM2 Antibody [DyLight 405] - NB110-81601V from Novus Biologicals

Prices $319.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TRPM2 Antibody [DyLight 650] - NB110-81601C from Novus Biologicals

Prices $319.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TRPM2 Antibody [DyLight 550] - NB110-81601R from Novus Biologicals

Prices $319.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TRPM2 Antibody [DyLight 488] - NB110-81601G from Novus Biologicals

Prices $319.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TRPM2 Antibody [Biotin] - NB110-81601B from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TRPM2 Antibody [HRP] - NB110-81601H from Novus Biologicals

Prices $319.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TRPM2 Antibody [Alexa Fluor (R) 700] - NB110-82364AF700 from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rabbit
Clonality Polyclonal

TRPM2 Antibody [Alexa Fluor (R) 647] - NB110-82364AF647 from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rabbit
Clonality Polyclonal

TRPM2 Antibody [Alexa Fluor (R) 488] - NB110-82364AF488 from Novus Biologicals

Prices $329.00
Sizes 100 tests
Host Rabbit
Clonality Polyclonal

TRPM2 Antibody [Alexa Fluor (R) 405] - NB110-82364AF405 from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rabbit
Clonality Polyclonal

TRPM2 Antibody [DyLight 550] - NB110-82364R from Novus Biologicals

Prices $319.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TRPM2 Antibody [DyLight 488] - NB110-82364G from Novus Biologicals

Prices $319.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TRPM2 Antibody [HRP] - NB110-82364H from Novus Biologicals

Prices $319.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TRPM2 Antibody [DyLight 650] - NB110-82364C from Novus Biologicals

Prices $319.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TRPM2 Antibody [Biotin] - NB110-82364B from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TRPM2 Antibody [FITC] - NB110-82364F from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TRPM2 Antibody [DyLight 405] - NB110-82364V from Novus Biologicals

Prices $319.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TRPM2-Antibody - AG1344 from Abgent, a WuXi AppTec company

Prices $475.00, $575.00
Sizes 50 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of rat lung membrane (lanes 1 and 4), rat brain membrane (lanes 2 and 5) and human K562 cells (lanes 3 and 6) lysates: 1-3. Anti-TRPM2 antibody (#AG1344), (1:200). 4-6. Anti-TRPM2 antibody, preincubated with the control peptide antigen.
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