Ggt1

Gene Symbol Ggt1
Entrez Gene 116568
Alt Symbol GGLUT, Ggt, Ggtp
Species Rat
Gene Type protein-coding
Description gamma-glutamyltransferase 1
Other Description GGT 1|gamma glutamyl-transferase 1|gamma-glutamyl transpeptidase|gamma-glutamyltranspeptidase 1|glutathione hydrolase 1|leukotriene-C4 hydrolase
Swissprots Q63218 Q6AZ32 Q63217 P07314
Accessions AAA41217 EDL97199 EDL97200 EDL97201 EDL97202 EDL97203 EDL97204 EDL97205 EDL97206 EDL97207 EDL97208 EDL97209 EDL97210 EDL97211 EDL97212 P07314 BC078768 AAH78768 M33821 AAA57295 M33822 AAB59698 X15443 CAA33483 NM_053840 NP_446292
Function Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide, cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity Detected in adult kidney and mammary gland, and in fetal liver.
Top Pathways Taurine and hypotaurine metabolism, Glutathione metabolism, Arachidonic acid metabolism, Cyanoamino acid metabolism

Rat-Ggt1-AntibodyN-term - AP19641a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Rat Ggt1 Antibody (N-term) (Cat. #AP19641a) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Rat Ggt1 antibody detected the Rat Ggt1 protein (arrow).

Rat Ggt1 Antibody - N-terminal region (OAAB15160) - OAAB15160 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-Rat Ggt1(N-term) - 102-14361 from RayBiotech

Host Rabbit
Rat Ggt1 Antibody (N-term) (Cat# 102-14361) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Rat Ggt1 antibody detected the Rat Ggt1 protein (arrow).

Rat Ggt1 antibody (N-term) - STJ47640 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal
Clone RB40721

GGT1 Antibody, Rabbit PAb - 80364-RP01-200 from Sino Biological

Prices $230.00, $230.00
Sizes 100 µg, 200 µg
Host Rabbit
Clonality Polyclonal

GGT1 Antibody, Rabbit PAb, Antigen Affinity Purified - 80364-T24-100 from Sino Biological

Prices $170.00, $290.00
Sizes 50 µg, 100 µg
Host Rabbit
Clonality Polyclonal

Ggt1, Polyclonal Antibody - MBS9202230 from MyBioSource

Prices $155.00, $340.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal

GGT1 antibody - orb232017 from Biorbyt

Prices $323.00, $442.00, $570.00
Sizes 50 μg, 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal

Ggt1 antibody - orb166359 from Biorbyt

Prices $187.00, $383.00
Sizes 80 μl (Trial size), 400 μl
Host Rabbit
Clonality Polyclonal
Clone RB40721

CD224 antibody - orb171431 from Biorbyt

Prices $323.00, $442.00, $570.00
Sizes 100 μg, 200 μg, 400 μg
Host Rabbit
Clonality Polyclonal

GGT1 Antibody, Rabbit PAb, Antigen Affinity Purified - 80364-T24-200 from Sino Biological

Host Rabbit
Clonality Polyclonal
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