Gene Symbol | GLDN |
---|---|
Entrez Gene | 342035 |
Alt Symbol | CLOM, COLM, CRG-L2, CRGL2, UNC-112 |
Species | Human |
Gene Type | protein-coding |
Description | gliomedin |
Other Description | collomin|colmedin |
Swissprots | Q6ZMI3 Q7Z359 Q6UXZ7 |
Accessions | EAW77418 EAW77419 Q6ZMI3 AK023623 AK095128 AK172756 BAD18742 AK308933 AK310755 AY358144 AAQ88511 BC113397 AAI13398 BC113399 AAI13400 BK001262 DAA01143 BX538105 CAD98018 XM_011521501 XP_011519803 NM_181789 NP_861454 |
Function | Plays a role in the formation of the nodes of Ranvier along myelinated axons. Probable NRCAM and NFASC/neurofascin ligand which may provide a glial positional clue required for the proper molecular assembly of the nodes of Ranvier (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane; Single-pass type II membrane protein. Note=Localizes to the nodes of Ranvier. {ECO:0000250}. |
Tissue Specificity | Specifically expressed in spinal cord, brain, placenta and sciatic nerve. More abundant in peripheral than central nervous system. {ECO:0000269|PubMed:16039564}. |