Gene Symbol | GLDN |
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Entrez Gene | 342035 |
Alt Symbol | CLOM, COLM, CRG-L2, CRGL2, UNC-112 |
Species | Human |
Gene Type | protein-coding |
Description | gliomedin |
Other Description | collomin|colmedin |
Swissprots | Q6ZMI3 Q7Z359 Q6UXZ7 |
Accessions | EAW77418 EAW77419 Q6ZMI3 AK023623 AK095128 AK172756 BAD18742 AK308933 AK310755 AY358144 AAQ88511 BC113397 AAI13398 BC113399 AAI13400 BK001262 DAA01143 BX538105 CAD98018 XM_011521501 XP_011519803 NM_181789 NP_861454 |
Function | Plays a role in the formation of the nodes of Ranvier along myelinated axons. Probable NRCAM and NFASC/neurofascin ligand which may provide a glial positional clue required for the proper molecular assembly of the nodes of Ranvier (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane; Single-pass type II membrane protein. Note=Localizes to the nodes of Ranvier. {ECO:0000250}. |
Tissue Specificity | Specifically expressed in spinal cord, brain, placenta and sciatic nerve. More abundant in peripheral than central nervous system. {ECO:0000269|PubMed:16039564}. |
Gliomedin CRISPR/Cas9 KO Plasmid (h) - sc-407885 from Santa Cruz Biotechnology
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Gliomedin HDR Plasmid (h) - sc-407885-HDR from Santa Cruz Biotechnology
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Gliomedin Double Nickase Plasmid (h) - sc-407885-NIC from Santa Cruz Biotechnology
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Gliomedin Double Nickase Plasmid (h2) - sc-407885-NIC-2 from Santa Cruz Biotechnology
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Gliomedin CRISPR Activation Plasmid (h) - sc-407885-ACT from Santa Cruz Biotechnology
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Gliomedin CRISPR Activation Plasmid (h2) - sc-407885-ACT-2 from Santa Cruz Biotechnology
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Gliomedin Lentiviral Activation Particles (h) - sc-407885-LAC from Santa Cruz Biotechnology
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Gliomedin Lentiviral Activation Particles (h2) - sc-407885-LAC-2 from Santa Cruz Biotechnology
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Gliomedin siRNA (h) - sc-62378 from Santa Cruz Biotechnology
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Gliomedin shRNA Plasmid (h) - sc-62378-SH from Santa Cruz Biotechnology
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Gliomedin shRNA (h) Lentiviral Particles - sc-62378-V from Santa Cruz Biotechnology
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Gliomedin RNAi - H00342035-R01 from Novus Biologicals
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MISSION® esiRNA - EHU090331 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9336 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9336 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR13998 from Sigma-Aldrich
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GLDN siRNA (Human) - CRJ7389 from Cohesion Biosciences
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GLDN - MBS8226018 from MyBioSource
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shRNA set against Human Gldn (NM_181789.2) - SHH301702 from Creative biogene
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shRNA set against Human GLDN(NM_181789.2) - SHG198871 from Creative biogene
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Human GLDN siRNA - orb277890 from Biorbyt
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GLDN shRNA Plasmid (Human) - CHJ7389 from Cohesion Biosciences
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GLDN miRNA 3'UTR clone - MiUTR1H-04059 from Creative biogene
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