CHST3

Gene Symbol CHST3
Entrez Gene 9469
Alt Symbol C6ST, C6ST1, HSD
Species Human
Gene Type protein-coding
Description carbohydrate (chondroitin 6) sulfotransferase 3
Other Description C6ST-1|GST-0|carbohydrate sulfotransferase 3|chondroitin 6-O-sulfotransferase 1|galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0
Swissprots O75099 Q52M30 Q7LGC8
Accessions EAW54440 Q7LGC8 AB012192 BAA32576 AB017915 BAA36348 AI041015 AK025251 BC033183 BC093690 AAH93690 BC104856 AAI04857 BG325090 DA223095 DB289525 XM_006718075 XP_006718138 XM_011540369 XP_011538671 NM_004273 NP_004264
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues of keratan sulfate, another glycosaminoglycan, and the Gal residues in sialyl N- acetyllactosamine (sialyl LacNAc) oligosaccharides. May play a role in the maintenance of naive T-lymphocytes in the spleen. {ECO:0000269|PubMed:9714738, ECO:0000269|PubMed:9883891}.
Subcellular Location Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity Widely expressed in adult tissues. Expressed in heart, placenta, skeletal muscle and pancreas. Also expressed in various immune tissues such as spleen, lymph node, thymus and appendix. {ECO:0000269|PubMed:9714738}.
Top Pathways Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate

C6ST-1 CRISPR/Cas9 KO Plasmid (h) - sc-407409 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C6ST-1 HDR Plasmid (h) - sc-407409-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C6ST-1 Double Nickase Plasmid (h) - sc-407409-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C6ST-1 Double Nickase Plasmid (h2) - sc-407409-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C6ST-1 CRISPR Activation Plasmid (h) - sc-407409-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C6ST-1 CRISPR Activation Plasmid (h2) - sc-407409-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C6ST-1 Lentiviral Activation Particles (h) - sc-407409-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C6ST-1 Lentiviral Activation Particles (h2) - sc-407409-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C6ST-1 siRNA (h) - sc-60305 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

C6ST-1 shRNA Plasmid (h) - sc-60305-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

C6ST-1 shRNA (h) Lentiviral Particles - sc-60305-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Carbohydrate Sulfotransferase 3/CHST3 RNAi - H00009469-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN6111 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6111 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CHST3 siRNA (Human) - CRH6285 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CHST3 - MBS8217505 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CHST3 (NM_004273.4) - SHH263801 from Creative biogene

Category siRNA
Species Reactivities Human

CHST3 shRNA Plasmid (Human) - CHH6285 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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