ACMSD

Gene Symbol ACMSD
Entrez Gene 130013
Alt Symbol -
Species Human
Gene Type protein-coding
Description aminocarboxymuconate semialdehyde decarboxylase
Other Description 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase|picolinate carboxylase
Swissprots Q8TDX5 Q96KY2 Q3B7X3 Q53SR5
Accessions AAY14997 EAX11649 EAX11650 EAX11651 EAX11652 Q8TDX5 AB071418 BAB86938 AK125008 BAC86023 BC016018 AAH16018 BC107420 AAI07421 BG428338 XM_005263586 XP_005263643 XM_005263587 XP_005263644 XM_005263588 XP_005263645 XM_005263589 XP_005263646 XM_005263590 XP_005263647 XM_011510592 XP_011508894 NM_001307983 NP_001294912 NM_138326 NP_612199
Function Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway. {ECO:0000269|PubMed:19843166}.
Top Pathways Tryptophan metabolism

ACMSD (G-12) - sc-107372 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ACMSD (K-14) - sc-107373 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ACMSD (K-14): sc-107373. Western blot analysis of ACMSD expression in mouse kidney (A) and human liaver (B) tissue extracts.

Anti-ACMSD antibody - ab58015 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab58015 ACMSD antibody at 1ug/ml.

Anti-ACMSD Antibody (aa179-279) - LS-C306053 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-ACMSD Antibody (aa251-300) - LS-C111059 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ACMSD antibody LS-C111059 Western blot of Fetal Kidney lysate.

Anti-ACMSD Antibody (aa105-336) - LS-C185833 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded SAS xenograft using ACMSD antibody at 1:100 dilution.

ACMSD Antibody - NBP1-86480 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ACMSD Antibody [NBP1-86480] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

ACMSD Antibody - NBP1-33499 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ACMSD Antibody [NBP1-33499] - Sample (30 ug of whole cell lysate) A: Molt-4 B: Raji 10% SDS PAGE; antibody diluted at 1:1000.

ACMSD Antibody - NBP1-86108 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ACMSD Antibody [NBP1-86108] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells), Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells).

ACMSD Antibody - H00130013-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: ACMSD Antibody [H00130013-A01] - Western Blot analysis of ACMSD expression in HepG2 ( Cat # L019V1 ).

ACMSD Antibody (3A9) - H00130013-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3A9
Western Blot: ACMSD Antibody (3A9) [H00130013-M01] - Analysis of ACMSD expression in transfected 293T cell line by ACMSD monoclonal antibody (M01), clone 3A9.Lane 1: ACMSD transfected lysate (Predicted MW: 31.2 KDa).Lane 2: Non-transfected lysate.

Anti-ACMSD antibody produced in rabbit - HPA010533 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ACMSD: <B>Cat. No. HPA010533</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney shows strong nuclear and cytoplasmic positivity in cells of tubules.

Anti-ACMSD antibody produced in rabbit - SAB2105645 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ACMSD: <B>Cat. No. SAB2105645</B>: ACMSD in Fetal Kidney cell lysates with ACMSD antibody at 1.0 μg/mL.

Anti-ACMSD antibody produced in rabbit - HPA011179 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ACMSD: <B>Cat. No. HPA011179</B>: Immunohistochemical staining of human kidney shows strong cytoplasmic positivity in cells in tubules.

Monoclonal Anti-ACMSD antibody produced in mouse - WH0130013M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3A9
<B>Immunoblotting</B><BR/>Monoclonal Anti-ACMSD, <B>Cat. No. WH0130013M1</B> used at the antibody concentration: 1 μg/mL. Specific band of ~37.11 kDa using immunogen protein lysate.

ACMSD antibody - middle region (ARP45728_P050) - ARP45728_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ACMSD antibody [N2C3] - GTX106739 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-ACMSD antibody [N2C3] used in Western blot. GTX106739

Anti -ACMSD (Picolinate Carboxylase, 2-amino-3-carboxymuconate-6-semialdehydeDecarboxylase) - 122875 from USBiological Life Science

Host Mouse
Clonality Monoclonal
Clone 3A9

Anti -ACMSD (Picolinate Carboxylase, 2-amino-3-carboxymuconate-6-semialdehydeDecarboxylase) (AP) - 122875-AP from USBiological Life Science

Host Mouse
Clonality Monoclonal
Clone 3A9

Anti -ACMSD (Picolinate Carboxylase, 2-amino-3-carboxymuconate-6-semialdehydeDecarboxylase) (FITC) - 122875-FITC from USBiological Life Science

Host Mouse
Clonality Monoclonal
Clone 3A9

Anti -ACMSD (Picolinate Carboxylase, 2-amino-3-carboxymuconate-6-semialdehydeDecarboxylase) (HRP) - 122875-HRP from USBiological Life Science

Host Mouse
Clonality Monoclonal
Clone 3A9

Anti -ACMSD (Picolinate Carboxylase, 2-amino-3-carboxymuconate-6-semialdehydeDecarboxylase) (PE) - 122875-PE from USBiological Life Science

Host Mouse
Clonality Monoclonal
Clone 3A9

ACMSD antibody - orb69803 from Biorbyt

Prices $723.00
Sizes 100 μl
Host Rabbit
Clonality Polyclonal
Western Blot analysis of A:Molt4, B:Raji whole cell lysate using ACMSD antibody

ACMSD antibody - orb77650 from Biorbyt

Prices $425.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of Hela cell lysate using ACMSD antibody
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