Gene Symbol | Kras |
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Entrez Gene | 16653 |
Alt Symbol | AI929937, K-ras, Ki-ras, Kras-2, Kras2, p21B, ras |
Species | Mouse |
Gene Type | protein-coding |
Description | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog |
Other Description | GTPase KRas|K-Ras 2|Kirsten rat sarcoma oncogene 2, expressed|c-K-ras|c-Ki-ras|p21 protein |
Swissprots | P08643 P04200 P32883 |
Accessions | AAA40037 AAO46052 CAA26295 CAA26296 CAA33897 CDL93478 EDL10686 P32883 AK155064 BAE33023 AK164065 BAE37609 AY487807 AAS58056 BC004642 AAH04642 BC010202 AAH10202 BC014700 BC031623 BC119495 AAI19496 BC141051 AAI41052 U76425 U76426 X00485 CAA25160 XM_006506918 XP_006506981 XM_006506919 XP_006506982 XM_006536039 XP_006536102 XM_006536040 XP_006536103 NM_021284 NP_067259 |
Function | Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation (PubMed:6474169, PubMed:1352876). {ECO:0000250|UniProtKB:P01116, ECO:0000269|PubMed:1352876, ECO:0000269|PubMed:6474169}. |
Subcellular Location | Cell membrane {ECO:0000250|UniProtKB:P01116}; Lipid-anchor {ECO:0000250|UniProtKB:P01116}; Cytoplasmic side {ECO:0000250|UniProtKB:P01116}. Cytoplasm {ECO:0000250|UniProtKB:P01116}. |
Top Pathways | Axon guidance, Tight junction, VEGF signaling pathway, Gap junction, Natural killer cell mediated cytotoxicity |
K-Ras CRISPR/Cas9 KO Plasmid (m) - sc-421333 from Santa Cruz Biotechnology
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K-Ras HDR Plasmid (m) - sc-421333-HDR from Santa Cruz Biotechnology
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K-Ras Double Nickase Plasmid (m) - sc-421333-NIC from Santa Cruz Biotechnology
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K-Ras Double Nickase Plasmid (m2) - sc-421333-NIC-2 from Santa Cruz Biotechnology
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K-Ras CRISPR Activation Plasmid (m) - sc-421333-ACT from Santa Cruz Biotechnology
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K-Ras CRISPR Activation Plasmid (m2) - sc-421333-ACT-2 from Santa Cruz Biotechnology
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K-Ras Lentiviral Activation Particles (m) - sc-421333-LAC from Santa Cruz Biotechnology
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K-Ras Lentiviral Activation Particles (m2) - sc-421333-LAC-2 from Santa Cruz Biotechnology
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K-Ras siRNA (m) - sc-43876 from Santa Cruz Biotechnology
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K-Ras shRNA Plasmid (m) - sc-43876-SH from Santa Cruz Biotechnology
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K-Ras shRNA (m) Lentiviral Particles - sc-43876-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN34459 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND34459 from Sigma-Aldrich
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KRAS siRNA (Mouse) - CRM2257 from Cohesion Biosciences
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shRNA set against Mouse KRAS (NM_021284.6) - SHH327103 from Creative biogene
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Mouse KRAS siRNA - orb281733 from Biorbyt
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KRAS shRNA Plasmid (Mouse) - CHM2257 from Cohesion Biosciences
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