| Gene Symbol |
SLC38A3
|
| Entrez Gene |
10991
|
| Alt Symbol |
G17, NAT1, SN1, SNAT3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 38, member 3
|
| Other Description |
N-system amino acid transporter 1|Na(+)-coupled neutral amino acid transporter 3|sodium-coupled neutral amino acid transporter 3|system N amino acid transporter 1|system N1 Na+ and H+-coupled glutamine transporter
|
| Swissprots |
Q6IB34 Q99624 B2R8Q0
|
| Accessions |
EAW65049 EAW65050 Q99624 AF244548 AAG15313 AK293801 BAH11599 AK299677 BAH13100 AK313461 BAG36247 AM392752 CAL37630 AM393543 CAL38420 BC042875 AAH42875 BM662099 BP362985 BX537382 CAD97624 CR456970 CAG33251 U49082 AAB47236 XM_006712954 XP_006713017 NM_006841 NP_006832
|
| Function |
Sodium-dependent amino acid/proton antiporter. Mediates electrogenic cotransport of glutamine and sodium ions in exchange for protons. Also recognizes histidine, asparagine and alanine. May mediate amino acid transport in either direction under physiological conditions. May play a role in nitrogen metabolism and synaptic transmission. {ECO:0000250|UniProtKB:Q9JHZ9, ECO:0000269|PubMed:10823827}.
|
| Subcellular Location |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Top Pathways |
Proximal tubule bicarbonate reclamation, GABAergic synapse, Glutamatergic synapse
|