Gene Symbol | SDCCAG3 |
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Entrez Gene | 10807 |
Alt Symbol | NY-CO-3 |
Species | Human |
Gene Type | protein-coding |
Description | serologically defined colon cancer antigen 3 |
Other Description | antigen NY-CO-3 |
Swissprots | Q5SXN8 Q5SXN4 Q5SXN3 A6NCP1 Q6V704 Q96C92 Q9NVY5 O60525 Q5SXN1 Q5SXN2 |
Accessions | EAW88228 EAW88229 EAW88230 EAW88231 Q96C92 AA742964 AF039688 AAC18037 AK001296 BAA91607 AL559847 AY129014 AAM98757 AY349357 AAQ56721 BC014515 AAH14515 BM549484 BQ723499 DQ893083 ABM84009 DQ896349 ABM87348 XM_005266050 XP_005266107 XM_005266051 XP_005266108 XM_011518156 XP_011516458 XM_011518157 XP_011516459 XR_929704 NM_001039707 NP_001034796 NM_001039708 NP_001034797 NM_006643 NP_006634 |
Function | May be involved in modulation of TNF response. May be involved in presentation of TNFRSF1A on the cell surface (By similarity). Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1 (PubMed:25278552). Involved in the regulation of cytokinesis; the function may involve PTPN13 and GIT1 (PubMed:23108400). {ECO:0000250|UniProtKB:A2AIW0, ECO:0000269|PubMed:23108400, ECO:0000269|PubMed:25278552}. |
Subcellular Location | Cytoplasm {ECO:0000250|UniProtKB:A2AIW0}. Midbody {ECO:0000269|PubMed:23108400}. Early endosome {ECO:0000269|PubMed:23108400}. Recycling endosome {ECO:0000269|PubMed:23108400}. Note=During cytokinesis colocalized with PTPN13 at the midbody (PubMed:23108400). Colocalizes in a FAM21-dependent manner with the retromer CSC complex at endosomes (PubMed:25278552). |
SDCCAG3 CRISPR/Cas9 KO Plasmid (h) - sc-410562 from Santa Cruz Biotechnology
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SDCCAG3 HDR Plasmid (h) - sc-410562-HDR from Santa Cruz Biotechnology
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SDCCAG3 Double Nickase Plasmid (h) - sc-410562-NIC from Santa Cruz Biotechnology
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SDCCAG3 Double Nickase Plasmid (h2) - sc-410562-NIC-2 from Santa Cruz Biotechnology
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SDCCAG3 CRISPR Activation Plasmid (h) - sc-410562-ACT from Santa Cruz Biotechnology
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SDCCAG3 CRISPR Activation Plasmid (h2) - sc-410562-ACT-2 from Santa Cruz Biotechnology
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SDCCAG3 Lentiviral Activation Particles (h) - sc-410562-LAC from Santa Cruz Biotechnology
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SDCCAG3 Lentiviral Activation Particles (h2) - sc-410562-LAC-2 from Santa Cruz Biotechnology
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SDCCAG3 siRNA (h) - sc-92784 from Santa Cruz Biotechnology
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SDCCAG3 shRNA Plasmid (h) - sc-92784-SH from Santa Cruz Biotechnology
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SDCCAG3 shRNA (h) Lentiviral Particles - sc-92784-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU114931 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18992 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18992 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06863 from Sigma-Aldrich
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SDCCAG3 siRNA (Human) - CRH7366 from Cohesion Biosciences
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SDCCAG3 - MBS8228441 from MyBioSource
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shRNA set against Human SDCCAG3 (NM_006643.3) - SHH403320 from Creative biogene
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shRNA set against Human SDCCAG3(NM_001039707.1) - SHR191666 from Creative biogene
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shRNA set against Human SDCCAG3(NM_006643.3) - SHR191748 from Creative biogene
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shRNA set against Human SDCCAG3(NM_001039707.1) - SHR191784 from Creative biogene
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shRNA set against Human SDCCAG3(NM_001039708.1) - SHR191850 from Creative biogene
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Human SDCCAG3 siRNA - orb267868 from Biorbyt
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SDCCAG3 shRNA Plasmid (Human) - CHH7366 from Cohesion Biosciences
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SDCCAG3 miRNA 3'UTR clone - MiUTR1H-09211 from Creative biogene
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