Gene Symbol |
CARTPT
|
Entrez Gene |
9607
|
Alt Symbol |
CART
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
CART prepropeptide
|
Other Description |
cocaine and amphetamine regulated transcript|cocaine- and amphetamine-regulated transcript protein
|
Swissprots |
Q6FG92 Q16568
|
Accessions |
AAB08011 EAW95694 Q16568 AI417979 BC029882 AAH29882 CK300473 CR542216 CAG47012 EU831800 ACE87318 EU831877 ACE86636 U16826 AAB08010 NM_004291 NP_004282
|
Function |
Satiety factor closely associated with the actions of leptin and neuropeptide y; this anorectic peptide inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide Y and regulated by leptin in the hypothalamus. It promotes neuronal development and survival in vitro. {ECO:0000269|PubMed:9590691}.
|
Subcellular Location |
Secreted {ECO:0000305}.
|
Tissue Specificity |
Hypothalamus. Found in neurons of the ventrolateral part of the arcuate nucleus, in the external zone of the median eminence, and also found in terminals in the periventricular part of the paraventricular nucleus.
|