Gene Symbol | CARTPT |
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Entrez Gene | 9607 |
Alt Symbol | CART |
Species | Human |
Gene Type | protein-coding |
Description | CART prepropeptide |
Other Description | cocaine and amphetamine regulated transcript|cocaine- and amphetamine-regulated transcript protein |
Swissprots | Q6FG92 Q16568 |
Accessions | AAB08011 EAW95694 Q16568 AI417979 BC029882 AAH29882 CK300473 CR542216 CAG47012 EU831800 ACE87318 EU831877 ACE86636 U16826 AAB08010 NM_004291 NP_004282 |
Function | Satiety factor closely associated with the actions of leptin and neuropeptide y; this anorectic peptide inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide Y and regulated by leptin in the hypothalamus. It promotes neuronal development and survival in vitro. {ECO:0000269|PubMed:9590691}. |
Subcellular Location | Secreted {ECO:0000305}. |
Tissue Specificity | Hypothalamus. Found in neurons of the ventrolateral part of the arcuate nucleus, in the external zone of the median eminence, and also found in terminals in the periventricular part of the paraventricular nucleus. |
CART CRISPR/Cas9 KO Plasmid (h) - sc-417375 from Santa Cruz Biotechnology
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CART HDR Plasmid (h) - sc-417375-HDR from Santa Cruz Biotechnology
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CART Double Nickase Plasmid (h) - sc-417375-NIC from Santa Cruz Biotechnology
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CART Double Nickase Plasmid (h2) - sc-417375-NIC-2 from Santa Cruz Biotechnology
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CART CRISPR Activation Plasmid (h) - sc-417375-ACT from Santa Cruz Biotechnology
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CART CRISPR Activation Plasmid (h2) - sc-417375-ACT-2 from Santa Cruz Biotechnology
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CART Lentiviral Activation Particles (h) - sc-417375-LAC from Santa Cruz Biotechnology
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CART Lentiviral Activation Particles (h2) - sc-417375-LAC-2 from Santa Cruz Biotechnology
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CART siRNA (h) - sc-43664 from Santa Cruz Biotechnology
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CART shRNA Plasmid (h) - sc-43664-SH from Santa Cruz Biotechnology
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CART shRNA (h) Lentiviral Particles - sc-43664-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU011701 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5375 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5375 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03171 from Sigma-Aldrich
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CARTPT siRNA (Human) - CRH6392 from Cohesion Biosciences
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CARTPT - MBS8232632 from MyBioSource
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shRNA set against Human CARTPT (NM_004291.3) - SHH254817 from Creative biogene
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Human CARTPT siRNA - orb266894 from Biorbyt
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CARTPT shRNA Plasmid (Human) - CHH6392 from Cohesion Biosciences
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CARTPT miRNA 3'UTR clone - MiUTR4H-TG01624 from Creative biogene
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