Gene Symbol | KRTAP3-3 |
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Entrez Gene | 85293 |
Alt Symbol | KAP3.3, KRTAP3.3 |
Species | Human |
Gene Type | protein-coding |
Description | keratin associated protein 3-3 |
Other Description | high sulfur keratin-associated protein 3.3|keratin-associated protein 3-3|keratin-associated protein 3.3 |
Swissprots | Q6NTD4 Q9BYR6 Q52LP0 |
Accessions | EAW60693 Q9BYR6 AJ406933 CAC27572 BC069099 AAH69099 BC069448 AAH69448 BC093845 AAH93845 BC093847 AAH93847 HQ448442 ADQ32922 NM_033185 NP_149441 |
Function | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. |
Tissue Specificity | Localized to the upper cortex of the hair shaft. {ECO:0000269|PubMed:11279113}. |
KRTAP3-3 CRISPR/Cas9 KO Plasmid (h) - sc-417381 from Santa Cruz Biotechnology
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KRTAP3-3 HDR Plasmid (h) - sc-417381-HDR from Santa Cruz Biotechnology
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KRTAP3-3 Double Nickase Plasmid (h) - sc-417381-NIC from Santa Cruz Biotechnology
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KRTAP3-3 Double Nickase Plasmid (h2) - sc-417381-NIC-2 from Santa Cruz Biotechnology
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KRTAP3-3 CRISPR Activation Plasmid (h) - sc-417381-ACT from Santa Cruz Biotechnology
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KRTAP3-3 CRISPR Activation Plasmid (h2) - sc-417381-ACT-2 from Santa Cruz Biotechnology
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KRTAP3-3 Lentiviral Activation Particles (h) - sc-417381-LAC from Santa Cruz Biotechnology
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KRTAP3-3 Lentiviral Activation Particles (h2) - sc-417381-LAC-2 from Santa Cruz Biotechnology
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KRTAP3-3 siRNA (h) - sc-93852 from Santa Cruz Biotechnology
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KRTAP3-3 shRNA Plasmid (h) - sc-93852-SH from Santa Cruz Biotechnology
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KRTAP3-3 shRNA (h) Lentiviral Particles - sc-93852-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU228641 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11468 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11468 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03578 from Sigma-Aldrich
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KRTAP3-3 siRNA (Human) - CRJ3770 from Cohesion Biosciences
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shRNA set against Human KRTAP3-3(NM_033185.2) - SHH139511 from Creative biogene
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Human KRTAP3-3 siRNA - orb274271 from Biorbyt
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KRTAP3-3 shRNA Plasmid (Human) - CHJ3770 from Cohesion Biosciences
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KRTAP3-3 miRNA 3'UTR clone - MiUTR1H-05515 from Creative biogene
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