| Gene Symbol |
CNIH1
|
| Entrez Gene |
10175
|
| Alt Symbol |
CNIH, CNIH-1, CNIL, TGAM77
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cornichon family AMPA receptor auxiliary protein 1
|
| Other Description |
T-cell growth-associated molecule 77|cornichon homolog|protein cornichon homolog 1
|
| Swissprots |
Q3SYM7 O95406
|
| Accessions |
CAF85952 EAW80635 EAW80636 EAW80637 O95406 AF070654 AAD20960 AF104398 AAC98388 AK022936 AK074781 BAG52000 AK307074 AK311897 BAG34838 AY358635 AAQ88998 BC103741 AAI03742 BG503618 BQ233425 BQ937490 BX248284 CAD62612 NM_001009551 NM_005776 NP_005767
|
| Function |
Involved in the selective transport and maturation of TGF-alpha family proteins. {ECO:0000269|PubMed:17607000}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:17607000}; Multi-pass membrane protein {ECO:0000269|PubMed:17607000}. Golgi apparatus membrane {ECO:0000269|PubMed:17607000}. Note=Located primarily in the ER; may cycle between the ER and the Golgi apparatus.
|
| Tissue Specificity |
Highly expressed in heart, liver, skeletal muscle, pancreas, adrenal medulla and cortex, thyroid, testis, spleen, appendix, peripheral blood lymphocytes and bone marrow. Lower expression found in brain, placenta, lung, kidney, ovary, small intestine, stomach, lymph node, thymus and fetal liver. Expression is up-regulated in dorsolateral prefrontal cortex of patients with schizophrenia (postmortem brain study). {ECO:0000269|PubMed:23103966}.
|