Gene Symbol | CNIH1 |
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Entrez Gene | 10175 |
Alt Symbol | CNIH, CNIH-1, CNIL, TGAM77 |
Species | Human |
Gene Type | protein-coding |
Description | cornichon family AMPA receptor auxiliary protein 1 |
Other Description | T-cell growth-associated molecule 77|cornichon homolog|protein cornichon homolog 1 |
Swissprots | Q3SYM7 O95406 |
Accessions | CAF85952 EAW80635 EAW80636 EAW80637 O95406 AF070654 AAD20960 AF104398 AAC98388 AK022936 AK074781 BAG52000 AK307074 AK311897 BAG34838 AY358635 AAQ88998 BC103741 AAI03742 BG503618 BQ233425 BQ937490 BX248284 CAD62612 NM_001009551 NM_005776 NP_005767 |
Function | Involved in the selective transport and maturation of TGF-alpha family proteins. {ECO:0000269|PubMed:17607000}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:17607000}; Multi-pass membrane protein {ECO:0000269|PubMed:17607000}. Golgi apparatus membrane {ECO:0000269|PubMed:17607000}. Note=Located primarily in the ER; may cycle between the ER and the Golgi apparatus. |
Tissue Specificity | Highly expressed in heart, liver, skeletal muscle, pancreas, adrenal medulla and cortex, thyroid, testis, spleen, appendix, peripheral blood lymphocytes and bone marrow. Lower expression found in brain, placenta, lung, kidney, ovary, small intestine, stomach, lymph node, thymus and fetal liver. Expression is up-regulated in dorsolateral prefrontal cortex of patients with schizophrenia (postmortem brain study). {ECO:0000269|PubMed:23103966}. |
CNIH CRISPR/Cas9 KO Plasmid (h) - sc-407299 from Santa Cruz Biotechnology
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CNIH HDR Plasmid (h) - sc-407299-HDR from Santa Cruz Biotechnology
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CNIH Double Nickase Plasmid (h) - sc-407299-NIC from Santa Cruz Biotechnology
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CNIH Double Nickase Plasmid (h2) - sc-407299-NIC-2 from Santa Cruz Biotechnology
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CNIH CRISPR Activation Plasmid (h) - sc-407299-ACT from Santa Cruz Biotechnology
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CNIH CRISPR Activation Plasmid (h2) - sc-407299-ACT-2 from Santa Cruz Biotechnology
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CNIH Lentiviral Activation Particles (h) - sc-407299-LAC from Santa Cruz Biotechnology
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CNIH Lentiviral Activation Particles (h2) - sc-407299-LAC-2 from Santa Cruz Biotechnology
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CNIH siRNA (h) - sc-92298 from Santa Cruz Biotechnology
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CNIH shRNA Plasmid (h) - sc-92298-SH from Santa Cruz Biotechnology
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CNIH shRNA (h) Lentiviral Particles - sc-92298-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU048251 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6303 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6303 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07090 from Sigma-Aldrich
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CNIH1 siRNA (Human) - CRH6872 from Cohesion Biosciences
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CNIH1 - MBS8232481 from MyBioSource
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shRNA set against Human CNIH (NM_005776.2) - SHH266225 from Creative biogene
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shRNA set against Human CNIH(NM_005776.2) - SHG186635 from Creative biogene
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CNIH1 shRNA Plasmid (Human) - CHH6872 from Cohesion Biosciences
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CNIH miRNA 3'UTR clone - MiUTR1H-02268 from Creative biogene
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