| Gene Symbol |
CLDN8
|
| Entrez Gene |
9073
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
claudin 8
|
| Other Description |
claudin-8
|
| Swissprots |
D3DSE3 Q53EX7 P56748
|
| Accessions |
BAA95567 CAB60615 CAI93554 EAX09901 EAX09902 P56748 AK022269 BAG51070 AK223512 BAD97232 AL049977 AW235670 AY358707 AAQ89070 BC020866 AAH20866 BC058004 AAH58004 DA629490 DQ892002 ABM82928 DQ895192 ABM86118 NM_199328 NP_955360 NM_012132
|
| Function |
Plays a major role in tight junction-specific obliteration of the intercellular space. {ECO:0000250}.
|
| Subcellular Location |
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. Note=Localizes to tight junctions in all 3 segments of the epididymis, in the caput found in the lateral margins of principal cells, and in the corpus at the interface between basal and principal cells.
|
| Tissue Specificity |
Expressed in the epididymis, mainly in the caput segment. {ECO:0000269|PubMed:17287494}.
|
| Top Pathways |
Tight junction, Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Hepatitis C
|