| Gene Symbol |
PLEKHA4
|
| Entrez Gene |
57664
|
| Alt Symbol |
PEPP1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
|
| Other Description |
PEPP-1|PH domain-containing family A member 4|phosphoinositol 3-phosphate binding protein-1|phosphoinositol 3-phosphate-binding PH domain protein 1|phosphoinositol 3-phosphate-binding protein 1|pleckstrin homology domain-containing family A member 4
|
| Swissprots |
Q9H4M7 Q8N658 Q8N4M8
|
| Accessions |
EAW52406 EAW52407 EAW52408 Q9H4M7 AB208908 BAD92145 AY007233 AAG01896 BC015956 BC024157 AAH24157 BC025259 BC033832 AAH33832 BC064601 AAH64601 DQ893434 ABM84360 EU176759 ABW03560 XM_005259107 XP_005259164 XM_006723301 XP_006723364 XM_011527157 XP_011525459 XM_011527158 XP_011525460 XM_011527159 XP_011525461 XM_011527160 XP_011525462 XM_011527161 XP_011525463 XM_011527162 XP_011525464 NM_001161354 NP_001154826 NM_020904 NP_065955
|
| Function |
Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides. {ECO:0000269|PubMed:11001876}.
|
| Subcellular Location |
Cytoplasm {ECO:0000305}. Membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Highly expressed in melanoma. Detected at low levels in heart, skeletal muscle, kidney, liver and small intestine. {ECO:0000269|PubMed:11001876}.
|