Gene Symbol | PLEKHA4 |
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Entrez Gene | 57664 |
Alt Symbol | PEPP1 |
Species | Human |
Gene Type | protein-coding |
Description | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 |
Other Description | PEPP-1|PH domain-containing family A member 4|phosphoinositol 3-phosphate binding protein-1|phosphoinositol 3-phosphate-binding PH domain protein 1|phosphoinositol 3-phosphate-binding protein 1|pleckstrin homology domain-containing family A member 4 |
Swissprots | Q9H4M7 Q8N658 Q8N4M8 |
Accessions | EAW52406 EAW52407 EAW52408 Q9H4M7 AB208908 BAD92145 AY007233 AAG01896 BC015956 BC024157 AAH24157 BC025259 BC033832 AAH33832 BC064601 AAH64601 DQ893434 ABM84360 EU176759 ABW03560 XM_005259107 XP_005259164 XM_006723301 XP_006723364 XM_011527157 XP_011525459 XM_011527158 XP_011525460 XM_011527159 XP_011525461 XM_011527160 XP_011525462 XM_011527161 XP_011525463 XM_011527162 XP_011525464 NM_001161354 NP_001154826 NM_020904 NP_065955 |
Function | Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides. {ECO:0000269|PubMed:11001876}. |
Subcellular Location | Cytoplasm {ECO:0000305}. Membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}. |
Tissue Specificity | Highly expressed in melanoma. Detected at low levels in heart, skeletal muscle, kidney, liver and small intestine. {ECO:0000269|PubMed:11001876}. |
PLEKHA4 CRISPR/Cas9 KO Plasmid (h) - sc-412869 from Santa Cruz Biotechnology
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PLEKHA4 HDR Plasmid (h) - sc-412869-HDR from Santa Cruz Biotechnology
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PLEKHA4 Double Nickase Plasmid (h) - sc-412869-NIC from Santa Cruz Biotechnology
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PLEKHA4 Double Nickase Plasmid (h2) - sc-412869-NIC-2 from Santa Cruz Biotechnology
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PLEKHA4 CRISPR Activation Plasmid (h) - sc-412869-ACT from Santa Cruz Biotechnology
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PLEKHA4 CRISPR Activation Plasmid (h2) - sc-412869-ACT-2 from Santa Cruz Biotechnology
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PLEKHA4 Lentiviral Activation Particles (h) - sc-412869-LAC from Santa Cruz Biotechnology
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PLEKHA4 Lentiviral Activation Particles (h2) - sc-412869-LAC-2 from Santa Cruz Biotechnology
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PLEKHA4 siRNA (h) - sc-97478 from Santa Cruz Biotechnology
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PLEKHA4 shRNA Plasmid (h) - sc-97478-SH from Santa Cruz Biotechnology
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PLEKHA4 shRNA (h) Lentiviral Particles - sc-97478-V from Santa Cruz Biotechnology
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PLEKHA4 RNAi - H00057664-R01 from Novus Biologicals
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MISSION® esiRNA - EHU133051 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16949 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16949 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00382 from Sigma-Aldrich
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PLEKHA4 siRNA (Human) - CRJ1617 from Cohesion Biosciences
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shRNA set against Human PLEKHA4 (NM_020904.2) - SHH377484 from Creative biogene
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PLEKHA4 shRNA Plasmid (Human) - CHJ1617 from Cohesion Biosciences
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PLEKHA4 miRNA 3'UTR clone - MiUTR3H-09462 from Creative biogene
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PLEKHA4 miRNA 3'UTR clone - MiUTR3H-09463 from Creative biogene
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