| Gene Symbol |
GRIN3B
|
| Entrez Gene |
116444
|
| Alt Symbol |
GluN3B, NR3B
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
|
| Other Description |
N-methyl-D-aspartate receptor subtype 3B|NMDA receptor subunit 3B|NMDA type glutamate receptor subunit NR3B|NMDAR3B|glutamate [NMDA] receptor subunit 3B|glutamate receptor ionotropic, NMDA 3B
|
| Swissprots |
Q5EAK7 Q7RTW9 O60391
|
| Accessions |
AAC12680 CAC69380 EAW69576 O60391 AY507106 AAS87020 AY507107 AAS87021 BC156390 AAI56391 BK000070 DAA00018 BK004079 DAA04570 CB243197 XM_011527669 XP_011525971 NM_138690 NP_619635
|
| Function |
NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine.
|
| Subcellular Location |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}. Note=Requires the presence of GRIN1 to be targeted at the plasma membrane. {ECO:0000250}.
|
| Top Pathways |
Glutamatergic synapse, Amphetamine addiction, Nicotine addiction, Cocaine addiction, Alcoholism
|