Gene Symbol |
PRPS1
|
Entrez Gene |
5631
|
Alt Symbol |
ARTS, CMTX5, DFN2, DFNX1, PPRibP, PRS-I, PRSI
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
phosphoribosyl pyrophosphate synthetase 1
|
Other Description |
dJ1070B1.2 (phosphoribosyl pyrophosphate synthetase 1)|deafness 2, perceptive, congenital|deafness, X-linked 2, perceptive, congenital|phosphoribosyl pyrophosphate synthase I|ribose-phosphate diphosphokinase 1|ribose-phosphate pyrophosphokinase 1
|
Swissprots |
B2R6T7 B1ALA8 D3DUX6 B4DNL6 P60891
|
Accessions |
AAD05560 BAA05675 EAX02709 EAX02710 EAX02711 P60891 AK223169 BAD96889 AK297968 BAG60278 AK307748 AK312706 BAG35584 AK316467 BAH14838 BC001605 AAH01605 D00860 BAA00733 DC411129 DQ895833 ABM86759 EU176362 ABW03813 X15331 CAA33386 NM_001204402 NP_001191331 NM_002764 NP_002755
|
Function |
Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
|
Top Pathways |
Pentose phosphate pathway, Purine metabolism, Biosynthesis of amino acids, Carbon metabolism
|