Gene Symbol | PRPS1 |
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Entrez Gene | 5631 |
Alt Symbol | ARTS, CMTX5, DFN2, DFNX1, PPRibP, PRS-I, PRSI |
Species | Human |
Gene Type | protein-coding |
Description | phosphoribosyl pyrophosphate synthetase 1 |
Other Description | dJ1070B1.2 (phosphoribosyl pyrophosphate synthetase 1)|deafness 2, perceptive, congenital|deafness, X-linked 2, perceptive, congenital|phosphoribosyl pyrophosphate synthase I|ribose-phosphate diphosphokinase 1|ribose-phosphate pyrophosphokinase 1 |
Swissprots | B2R6T7 B1ALA8 D3DUX6 B4DNL6 P60891 |
Accessions | AAD05560 BAA05675 EAX02709 EAX02710 EAX02711 P60891 AK223169 BAD96889 AK297968 BAG60278 AK307748 AK312706 BAG35584 AK316467 BAH14838 BC001605 AAH01605 D00860 BAA00733 DC411129 DQ895833 ABM86759 EU176362 ABW03813 X15331 CAA33386 NM_001204402 NP_001191331 NM_002764 NP_002755 |
Function | Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis. |
Top Pathways | Pentose phosphate pathway, Purine metabolism, Biosynthesis of amino acids, Carbon metabolism |
PRPS1 CRISPR/Cas9 KO Plasmid (h) - sc-410957 from Santa Cruz Biotechnology
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PRPS1 HDR Plasmid (h) - sc-410957-HDR from Santa Cruz Biotechnology
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PRPS1 Double Nickase Plasmid (h) - sc-410957-NIC from Santa Cruz Biotechnology
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PRPS1 Double Nickase Plasmid (h2) - sc-410957-NIC-2 from Santa Cruz Biotechnology
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PRPS1 CRISPR Activation Plasmid (h) - sc-410957-ACT from Santa Cruz Biotechnology
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PRPS1 CRISPR Activation Plasmid (h2) - sc-410957-ACT-2 from Santa Cruz Biotechnology
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PRPS1 Lentiviral Activation Particles (h) - sc-410957-LAC from Santa Cruz Biotechnology
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PRPS1 Lentiviral Activation Particles (h2) - sc-410957-LAC-2 from Santa Cruz Biotechnology
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PRPS1/2 siRNA (h) - sc-62894 from Santa Cruz Biotechnology
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PRPS1/2 shRNA Plasmid (h) - sc-62894-SH from Santa Cruz Biotechnology
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PRPS1/2 shRNA (h) Lentiviral Particles - sc-62894-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU109761 from Sigma-Aldrich
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MISSION® siRNA - SIHK1880 from Sigma-Aldrich
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MISSION® siRNA - SIHK1881 from Sigma-Aldrich
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MISSION® siRNA - SIHK1879 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2118 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2118 from Sigma-Aldrich
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PRPS1 siRNA (Human) - CRH3796 from Cohesion Biosciences
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shRNA set against Human PRPS1 (NM_002764.3) - SHH383876 from Creative biogene
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Human PRPS1 siRNA - orb264298 from Biorbyt
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PRPS1 shRNA Plasmid (Human) - CHH3796 from Cohesion Biosciences
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PRPS1 miRNA 3'UTR clone - MiUTR1H-08321 from Creative biogene
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