KCNK2

Gene Symbol	KCNK2
Entrez Gene	3776
Alt Symbol	K2p2.1, TPKC1, TREK, TREK-1, TREK1, hTREK-1c, hTREK-1e
Species	Human
Gene Type	protein-coding
Description	potassium channel, two pore domain subfamily K, member 2
Other Description	K2P2.1 potassium channel|TREK-1 K(+) channel subunit|TWIK-related potassium channel 1|outward rectifying potassium channel protein TREK-1|potassium channel subfamily K member 2|potassium channel subfamily k member 2 variant 1|potassium channel subfamily k member 2 variant 2|potassium inwardly-rectifying channel, subfamily K, member 2|tandem-pore-domain potassium channel TREK-1|two pore domain potassium channel TREK-1|two pore potassium channel TPKC1|two-pore potassium channel 1
Swissprots	Q5DP48 Q9UNE3 D3DTA5 B2RCS4 O95069 A8K618 B7ZL56 Q5DP47 A1Z1V3 Q9NRT2
Accessions	EAW93347 EAW93348 EAW93349 O95069 AF004711 AAD01203 AF129399 AAD47569 AF171068 AAF89743 AK123409 BAC85609 AK291483 BAF84172 AK294780 BAG57907 AK315249 BAG37671 AU280191 AY552980 AAT49015 AY552981 AAT49016 BC069462 AAH69462 BC101693 AAI01694 BC101695 AAI01696 BC143586 AAI43587 CD625291 CD625297 CD625301 DA475072 DR001358 EF165334 ABM47413 EF165335 ABM47414 KF182338 AGW27105 KF182339 AGW27106 XM_011509521 XP_011507823 XM_011509522 XP_011507824 XM_011509523 XP_011507825 XM_011509524 XP_011507826 NM_001017424 NP_001017424 NM_001017425 NP_001017425 NM_014217 NP_055032
Function	Reversibly converts between a voltage-insensitive potassium leak channel and a voltage-dependent outward rectifying potassium channel in a phosphorylation-dependent manner. {ECO:0000269|PubMed:10784345, ECO:0000269|PubMed:11319556, ECO:0000269|PubMed:24196565}.
Subcellular Location	Isoform 4: Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Tissue Specificity	Isoform 4 is detected in kidney, adrenal gland and brain where it is preferentially expressed in the amygdala but not found in thalamus, hypothalamus, hippocampus or substantia nigra. {ECO:0000269|PubMed:24196565}.
Top Pathways	Gastric acid secretion

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

TREK-1 (F-6) - sc-398449 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

TREK-1 (C-20) - sc-11557 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

TREK-1 (E-19) - sc-11556 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

TREK-1 (H-75) - sc-50412 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

TREK-1 (N-20) - sc-11554 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-KCNK2 antibody - ab83932 from Abcam Prices $379.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-KCNK2 / TREK-1 Antibody (N-Terminus) - LS-C46970 from LifeSpan Bioscience Prices $275.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-KCNK2 / TREK-1 Antibody (N-Terminus) - LS-C76523 from LifeSpan Bioscience Prices $495.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-KCNK2 / TREK-1 Antibody (aa4-14) - LS-C126403 from LifeSpan Bioscience Prices $435.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-KCNK2 / TREK-1 Antibody (N-Terminus, Biotin) - LS-C141398 from LifeSpan Bioscience Prices $365.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-KCNK2 / TREK-1 Antibody (N-Terminus, DY488) - LS-C141422 from LifeSpan Bioscience Prices $365.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-KCNK2 / TREK-1 Antibody (N-Terminus, DY650) - LS-C141399 from LifeSpan Bioscience Prices $365.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-KCNK2 / TREK-1 Antibody (N-Terminus, DY550) - LS-C141424 from LifeSpan Bioscience Prices $365.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-KCNK2 / TREK-1 Antibody (N-Terminus, HRP) - LS-C141423 from LifeSpan Bioscience Prices $365.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-KCNK2 / TREK-1 Antibody - LS-C146981 from LifeSpan Bioscience Prices $410.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-KCNK2 / TREK-1 Antibody (aa417) - LS-C190261 from LifeSpan Bioscience Prices $425.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-KCNK2 / TREK-1 Antibody (aa1-100) - LS-C49138 from LifeSpan Bioscience Prices $335.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

TREK 1 Antibody - NB110-41535 from Novus Biologicals Prices $299.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

TREK 1 Antibody [FITC] - NB110-41535F from Novus Biologicals Prices $299.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

TREK 1 Antibody [DyLight 405] - NB110-41535V from Novus Biologicals Prices $319.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

TREK 1 Antibody [Alexa Fluor (R) 700] - NB110-41535AF700 from Novus Biologicals Prices $319.00 Sizes 100 tests Host Rabbit Clonality Polyclonal

TREK 1 Antibody [Alexa Fluor (R) 647] - NB110-41535AF647 from Novus Biologicals Prices $319.00 Sizes 100 tests Host Rabbit Clonality Polyclonal

TREK 1 Antibody [Alexa Fluor (R) 488] - NB110-41535AF488 from Novus Biologicals Prices $329.00 Sizes 100 tests Host Rabbit Clonality Polyclonal

TREK 1 Antibody [Alexa Fluor (R) 405] - NB110-41535AF405 from Novus Biologicals Prices $319.00 Sizes 100 tests Host Rabbit Clonality Polyclonal

TREK 1 Antibody [DyLight 650] - NB110-41535C from Novus Biologicals Prices $319.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

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