| Gene Symbol |
UBE2Q2
|
| Entrez Gene |
92912
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ubiquitin-conjugating enzyme E2Q family member 2
|
| Other Description |
ubiquitin carrier protein Q2|ubiquitin-conjugating enzyme E2 Q2|ubiquitin-protein ligase Q2
|
| Swissprots |
Q8N4G6 H3BRG2 Q8WVN8 B7Z3Q2 Q96J08
|
| Accessions |
CCQ43122 EAW99233 EAW99234 Q8WVN8 AA476260 AK000617 AK294199 BAG57513 AK296234 BAH12288 AL117641 AL832429 CAH10654 BC006827 AAH06827 BC017708 AAH17708 BC034342 AAH34342 DR001046 HQ448230 ADQ32710 XM_005254787 XP_005254844 XM_005254788 XP_005254845 XM_006720770 XP_006720833 XM_011522227 XP_011520529 XM_011522228 XP_011520530 XR_931947 NM_001145335 NP_001138807 NM_001284382 NP_001271311 NM_173469 NP_775740
|
| Function |
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-linked polyubiquitination. {ECO:0000269|PubMed:20061386}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:16300736}.
|
| Tissue Specificity |
Detected in hypopharyngeal head and neck squamous cell carcinoma, in tumor masses and invasive epithelium. {ECO:0000269|PubMed:16300736}.
|
| Top Pathways |
Ubiquitin mediated proteolysis
|
![Western Blot: UBE2Q2 Overexpression Lysate (Adult Normal) [NBL1-17542] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for UBE2Q2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/10171_UBE2Q2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17542-img0002.jpg)