Gene Symbol | UBE2Q2 |
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Entrez Gene | 92912 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | ubiquitin-conjugating enzyme E2Q family member 2 |
Other Description | ubiquitin carrier protein Q2|ubiquitin-conjugating enzyme E2 Q2|ubiquitin-protein ligase Q2 |
Swissprots | Q8N4G6 H3BRG2 Q8WVN8 B7Z3Q2 Q96J08 |
Accessions | CCQ43122 EAW99233 EAW99234 Q8WVN8 AA476260 AK000617 AK294199 BAG57513 AK296234 BAH12288 AL117641 AL832429 CAH10654 BC006827 AAH06827 BC017708 AAH17708 BC034342 AAH34342 DR001046 HQ448230 ADQ32710 XM_005254787 XP_005254844 XM_005254788 XP_005254845 XM_006720770 XP_006720833 XM_011522227 XP_011520529 XM_011522228 XP_011520530 XR_931947 NM_001145335 NP_001138807 NM_001284382 NP_001271311 NM_173469 NP_775740 |
Function | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-linked polyubiquitination. {ECO:0000269|PubMed:20061386}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:16300736}. |
Tissue Specificity | Detected in hypopharyngeal head and neck squamous cell carcinoma, in tumor masses and invasive epithelium. {ECO:0000269|PubMed:16300736}. |
Top Pathways | Ubiquitin mediated proteolysis |
UBE2Q2 CRISPR/Cas9 KO Plasmid (h) - sc-413959 from Santa Cruz Biotechnology
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UBE2Q2 HDR Plasmid (h) - sc-413959-HDR from Santa Cruz Biotechnology
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UBE2Q2 Double Nickase Plasmid (h) - sc-413959-NIC from Santa Cruz Biotechnology
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UBE2Q2 Double Nickase Plasmid (h2) - sc-413959-NIC-2 from Santa Cruz Biotechnology
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UBE2Q2 CRISPR Activation Plasmid (h) - sc-413959-ACT from Santa Cruz Biotechnology
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UBE2Q2 CRISPR Activation Plasmid (h2) - sc-413959-ACT-2 from Santa Cruz Biotechnology
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UBE2Q2 Lentiviral Activation Particles (h) - sc-413959-LAC from Santa Cruz Biotechnology
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UBE2Q2 Lentiviral Activation Particles (h2) - sc-413959-LAC-2 from Santa Cruz Biotechnology
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UBE2Q2 siRNA (h) - sc-76792 from Santa Cruz Biotechnology
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UBE2Q2 shRNA Plasmid (h) - sc-76792-SH from Santa Cruz Biotechnology
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UBE2Q2 shRNA (h) Lentiviral Particles - sc-76792-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU068451 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22379 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22379 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10166 from Sigma-Aldrich
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UBE2Q2 siRNA (Human) - CRJ4174 from Cohesion Biosciences
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UBE2Q2 RNAi - H00092912-R01 from Novus Biologicals
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UBE2Q2 - MBS8221308 from MyBioSource
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shRNA set against Human UBE2Q2 (NM_173469.2) - SHH439132 from Creative biogene
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Human UBE2Q2 siRNA - orb274675 from Biorbyt
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UBE2Q2 shRNA Plasmid (Human) - CHJ4174 from Cohesion Biosciences
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UBE2Q2 miRNA 3'UTR clone - MiUTR3H-12478 from Creative biogene
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UBE2Q2 miRNA 3'UTR clone - MiUTR3H-12479 from Creative biogene
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