| Gene Symbol |
REG1A
|
| Entrez Gene |
5967
|
| Alt Symbol |
ICRF, P19, PSP, PSPS, PSPS1, PTP, REG
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
regenerating islet-derived 1 alpha
|
| Other Description |
REG-1-alpha|islet cells regeneration factor|islet of langerhans regenerating protein|lithostathine 1 alpha|lithostathine-1-alpha|pancreatic stone protein, secretory|pancreatic thread protein|protein-X|regenerating islet-derived protein 1-alpha|regenerating protein I alpha
|
| Swissprots |
P05451 P11379 Q4ZG28
|
| Accessions |
AAA36559 AAX88842 EAW99576 EAW99577 EAW99578 P05451 AF172331 AAD51330 AK291981 BAF84670 AK307292 AK311087 AW873911 BC005350 AAH05350 BC110438 AAI10439 BC118621 AAI18622 BM769434 M18963 AAA36558 M27190 AAA60546 W38384 NM_002909 NP_002900
|
| Function |
Might act as an inhibitor of spontaneous calcium carbonate precipitation. May be associated with neuronal sprouting in brain, and with brain and pancreas regeneration.
|
| Subcellular Location |
Secreted.
|
| Tissue Specificity |
In pancreatic acinar cells and, in lower levels, in brain. Enhanced expression of PSP-related transcripts and intraneuronal accumulation of PSP-like proteins is found in brain from Alzheimer disease and Down syndrome patients. {ECO:0000269|PubMed:2394826}.
|
![Western Blot: REG1 Overexpression Lysate (Adult Normal) [NBL1-15271] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for REG1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8987_REG1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-15271-img0002.jpg)