| Gene Symbol |
MED31
|
| Entrez Gene |
51003
|
| Alt Symbol |
3110004H13Rik, CGI-125, Soh1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
mediator complex subunit 31
|
| Other Description |
hSOH1|mediator complex subunit SOH1|mediator of RNA polymerase II transcription subunit 31|mediator of RNA polymerase II transcription, subunit 31 homolog
|
| Swissprots |
Q9Y3C7 B2R4L9
|
| Accessions |
EAW90301 Q9Y3C7 AF151883 AAD34120 AK094033 AK130946 AK311875 BAG34816 BC012539 AAH12539 JF432553 ADZ15770 NM_016060 NP_057144
|
| Function |
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
|
| Subcellular Location |
Nucleus {ECO:0000305}.
|