Gene Symbol | MED31 |
---|---|
Entrez Gene | 51003 |
Alt Symbol | 3110004H13Rik, CGI-125, Soh1 |
Species | Human |
Gene Type | protein-coding |
Description | mediator complex subunit 31 |
Other Description | hSOH1|mediator complex subunit SOH1|mediator of RNA polymerase II transcription subunit 31|mediator of RNA polymerase II transcription, subunit 31 homolog |
Swissprots | Q9Y3C7 B2R4L9 |
Accessions | EAW90301 Q9Y3C7 AF151883 AAD34120 AK094033 AK130946 AK311875 BAG34816 BC012539 AAH12539 JF432553 ADZ15770 NM_016060 NP_057144 |
Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
Subcellular Location | Nucleus {ECO:0000305}. |
Med31 CRISPR/Cas9 KO Plasmid (h) - sc-406599 from Santa Cruz Biotechnology
|
||||||||
Med31 HDR Plasmid (h) - sc-406599-HDR from Santa Cruz Biotechnology
|
||||||||
Med31 Double Nickase Plasmid (h) - sc-406599-NIC from Santa Cruz Biotechnology
|
||||||||
Med31 Double Nickase Plasmid (h2) - sc-406599-NIC-2 from Santa Cruz Biotechnology
|
||||||||
Med31 CRISPR Activation Plasmid (h) - sc-406599-ACT from Santa Cruz Biotechnology
|
||||||||
Med31 CRISPR Activation Plasmid (h2) - sc-406599-ACT-2 from Santa Cruz Biotechnology
|
||||||||
Med31 Lentiviral Activation Particles (h) - sc-406599-LAC from Santa Cruz Biotechnology
|
||||||||
Med31 Lentiviral Activation Particles (h2) - sc-406599-LAC-2 from Santa Cruz Biotechnology
|
||||||||
Med31 siRNA (h) - sc-93999 from Santa Cruz Biotechnology
|
||||||||
Med31 shRNA Plasmid (h) - sc-93999-SH from Santa Cruz Biotechnology
|
||||||||
Med31 shRNA (h) Lentiviral Particles - sc-93999-V from Santa Cruz Biotechnology
|
||||||||
MED31 RNAi - H00051003-R01 from Novus Biologicals
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN13180 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13180 from Sigma-Aldrich
|
||||||||
MED31 siRNA (Human) - CRH9445 from Cohesion Biosciences
|
||||||||
shRNA set against Human MED31 (NM_016060.2) - SHH340107 from Creative biogene
|
||||||||
shRNA set against Human MED31(NM_016060.2) - SHH183575 from Creative biogene
|
||||||||
Human MED31 siRNA - orb269947 from Biorbyt
|
||||||||
MED31 shRNA Plasmid (Human) - CHH9445 from Cohesion Biosciences
|
||||||||
MED31 miRNA 3'UTR clone - MiUTR1H-06191 from Creative biogene
|