Gene Symbol | PCK2 |
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Entrez Gene | 5106 |
Alt Symbol | PEPCK, PEPCK-M, PEPCK2 |
Species | Human |
Gene Type | protein-coding |
Description | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
Other Description | PEP carboxykinase|phosphoenolpyruvate carboxykinase [GTP], mitochondrial|phosphopyruvate carboxylase |
Swissprots | O43253 Q16822 Q9BV62 Q86U01 |
Accessions | BAD36844 CAA12234 CAA72272 EAW66115 Q16822 AK129934 AK301400 BAG62935 AK307913 AK311710 AK316206 BAH14577 BC001454 AAH01454 BQ957219 BU153045 BU623248 BX248272 CAD62600 CA444720 CN359636 CR456913 CAG33194 DA645036 DB028389 HY022221 X92720 CAA63380 XM_006720158 XP_006720221 XM_011536813 XP_011535115 NM_001018073 NP_001018083 NM_001291556 NP_001278485 NM_001308054 NP_001294983 NM_004563 NP_004554 |
Function | Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. {ECO:0000250}. |
Subcellular Location | Mitochondrion. |
Top Pathways | Glucagon signaling pathway, Glycolysis / Gluconeogenesis, AMPK signaling pathway, PI3K-Akt signaling pathway, Proximal tubule bicarbonate reclamation |
PCK2 (D3E11) Rabbit mAb - 8565 from Cell Signaling Technology
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PCK2 Antibody - 6924 from Cell Signaling Technology
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PEPCK (H-300) - sc-32879 from Santa Cruz Biotechnology
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PEPCK (P-16) - sc-28477 from Santa Cruz Biotechnology
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PEPCK-M (62-W) - sc-130388 from Santa Cruz Biotechnology
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PEPCK-M (C-21) - sc-130225 from Santa Cruz Biotechnology
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Anti-PCK2 antibody - ab70359 from Abcam
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Anti-PCK2 antibody - ab40843 from Abcam
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Anti-PCK2 antibody - ab137580 from Abcam
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Anti-PCK2 antibody - ab154247 from Abcam
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Anti-PCK2 antibody - ab77047 from Abcam
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Anti-PCK2 antibody [EPR14223(B)] - ab181170 from Abcam
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Anti-PCK2 antibody [EPR14224] - C-terminal - ab187145 from Abcam
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Anti-PCK2 antibody - C-terminal - ab71745 from Abcam
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Anti-PCK2 / PEPCK Antibody (clone 2C9) - LS-C197852 from LifeSpan Bioscience
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Anti-PCK2 / PEPCK Antibody (aa24-54) - LS-C101195 from LifeSpan Bioscience
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Anti-PCK2 / PEPCK Antibody (N-Terminus, AP) - LS-C280735 from LifeSpan Bioscience
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Anti-PCK2 / PEPCK Antibody (N-Terminus, APC) - LS-C280736 from LifeSpan Bioscience
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Anti-PCK2 / PEPCK Antibody (N-Terminus, Biotin) - LS-C280738 from LifeSpan Bioscience
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Anti-PCK2 / PEPCK Antibody (N-Terminus, FITC) - LS-C280739 from LifeSpan Bioscience
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Anti-PCK2 / PEPCK Antibody (N-Terminus, Azide-free, HRP) - LS-C280740 from LifeSpan Bioscience
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Anti-PCK2 / PEPCK Antibody (N-Terminus, PE) - LS-C280741 from LifeSpan Bioscience
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Anti-PCK2 / PEPCK Antibody (N-Terminus) - LS-C328183 from LifeSpan Bioscience
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Anti-PCK2 / PEPCK Antibody (aa407-419) - LS-C55245 from LifeSpan Bioscience
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PCK2 Antibody - NBP2-33606 from Novus Biologicals
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