| Gene Symbol |
GPR78
|
| Entrez Gene |
27201
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
G protein-coupled receptor 78
|
| Other Description |
G-protein coupled receptor 78
|
| Swissprots |
Q96P69 Q8NGV3
|
| Accessions |
BAC05898 CCQ43819 EAW82336 Q96P69 AF411107 AAL26479 AK128807 BAG54739 AK307281 AK308759 AK313038 BAG35871 AY359107 AAQ89465 BC057778 AAH57778 BC069343 AAH69343 BC069813 AAH69813 BE645298 JF810885 AEP43752 NM_080819 NP_543009 NR_045511
|
| Function |
Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. {ECO:0000269|PubMed:17363172}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
High level of expression in placenta. Expressed throughout the brain at low level. No expression detected in skeletal muscle, lung, heart, liver, pancreas, or kidney. {ECO:0000269|PubMed:17363172}.
|
![Western Blot: GPR78 Overexpression Lysate (Adult Normal) [NBL1-11293] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GPR78.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8635_GPR78%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11293-img0002.jpg)