Gene Symbol | GPR78 |
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Entrez Gene | 27201 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | G protein-coupled receptor 78 |
Other Description | G-protein coupled receptor 78 |
Swissprots | Q96P69 Q8NGV3 |
Accessions | BAC05898 CCQ43819 EAW82336 Q96P69 AF411107 AAL26479 AK128807 BAG54739 AK307281 AK308759 AK313038 BAG35871 AY359107 AAQ89465 BC057778 AAH57778 BC069343 AAH69343 BC069813 AAH69813 BE645298 JF810885 AEP43752 NM_080819 NP_543009 NR_045511 |
Function | Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. {ECO:0000269|PubMed:17363172}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | High level of expression in placenta. Expressed throughout the brain at low level. No expression detected in skeletal muscle, lung, heart, liver, pancreas, or kidney. {ECO:0000269|PubMed:17363172}. |
GPR78 CRISPR/Cas9 KO Plasmid (h) - sc-405837 from Santa Cruz Biotechnology
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GPR78 HDR Plasmid (h) - sc-405837-HDR from Santa Cruz Biotechnology
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GPR78 Double Nickase Plasmid (h) - sc-405837-NIC from Santa Cruz Biotechnology
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GPR78 Double Nickase Plasmid (h2) - sc-405837-NIC-2 from Santa Cruz Biotechnology
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GPR78 CRISPR Activation Plasmid (h) - sc-405837-ACT from Santa Cruz Biotechnology
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GPR78 CRISPR Activation Plasmid (h2) - sc-405837-ACT-2 from Santa Cruz Biotechnology
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GPR78 Lentiviral Activation Particles (h) - sc-405837-LAC from Santa Cruz Biotechnology
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GPR78 Lentiviral Activation Particles (h2) - sc-405837-LAC-2 from Santa Cruz Biotechnology
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GPR78 siRNA (h) - sc-75187 from Santa Cruz Biotechnology
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GPR78 shRNA Plasmid (h) - sc-75187-SH from Santa Cruz Biotechnology
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GPR78 shRNA (h) Lentiviral Particles - sc-75187-V from Santa Cruz Biotechnology
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GPR78 RNAi - H00027201-R02 from Novus Biologicals
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MISSION® esiRNA - EHU142451 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9617 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9617 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03111 from Sigma-Aldrich
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GPR78 siRNA (Human) - CRH9021 from Cohesion Biosciences
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GPR78 - MBS8218243 from MyBioSource
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shRNA set against Human GPR78 (NM_080819.4) - SHH307034 from Creative biogene
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GPR78 CRISPR/Cas9 KO Plasmid (h2) - sc-405837-KO-2 from Santa Cruz Biotechnology
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GPR78 HDR Plasmid (h2) - sc-405837-HDR-2 from Santa Cruz Biotechnology
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Human GPR78 siRNA - orb269523 from Biorbyt
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GPR78 shRNA Plasmid (Human) - CHH9021 from Cohesion Biosciences
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