Gene Symbol | Tfb1m |
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Entrez Gene | 224481 |
Alt Symbol | AI429207 |
Species | Mouse |
Gene Type | protein-coding |
Description | transcription factor B1, mitochondrial |
Other Description | S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1|dimethyladenosine transferase 1, mitochondrial|mitochondrial 12S rRNA dimethylase 1|mitochondrial transcription factor B1|mtTFB1 |
Swissprots | Q8JZM0 |
Accessions | EDL01644 Q8JZM0 AF508971 AAM33651 AK028212 AK217882 BC032930 AAH32930 XM_006523220 XP_006523283 XR_385130 NM_146074 NP_666186 |
Function | S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity (By similarity). {ECO:0000250}. |
Subcellular Location | Mitochondrion {ECO:0000250}. |
Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:12532263}. |
Recombinant Mouse Dimethyladenosine transferase 1, mitochondrial(Tfb1m) - CSB-YP023420MO CSB-EP023420MO CSB-BP023420MO CSB-MP023420MO from Cusabio
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Recombinant Mouse TFB1M Protein - TFB1M-16682M from Creative Biomart
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Dimethyladenosine transferase 1, mitochondrial (Tfb1m), Recombinant Protein - MBS1320845 from MyBioSource
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