| Gene Symbol |
NPY2R
|
| Entrez Gene |
4887
|
| Alt Symbol |
NPY2-R
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
neuropeptide Y receptor Y2
|
| Other Description |
NPY-Y2 receptor|neuropeptide Y receptor type 2
|
| Swissprots |
P49146 Q6AZZ6 Q9UE67 Q4W5G7 Q13457 Q13281
|
| Accessions |
AAC51115 AAD00248 AAO92062 AAY40940 EAX04901 P49146 BC075052 AAH75052 BC075053 AAH75053 U32500 AAA93170 U36269 AAC50281 U42389 AAB07760 U42766 AAB04120 XM_005263033 XP_005263090 XM_005263034 XP_005263091 NM_000910 NP_000901
|
| Function |
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu- 31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra.
|
| Top Pathways |
Neuroactive ligand-receptor interaction
|