| Gene Symbol | QRFPR |
|---|---|
| Entrez Gene | 84109 |
| Alt Symbol | AQ27, GPR103, SP9155 |
| Species | Human |
| Gene Type | protein-coding |
| Description | pyroglutamylated RFamide peptide receptor |
| Other Description | G protein-coupled receptor 103|G-protein coupled receptor 103|QRFP receptor|orexigenic neuropeptide QRFP receptor|peptide P518 receptor |
| Swissprots | Q96P65 |
| Accessions | EAX05261 EAX05262 Q96P65 AB109629 BAC98938 AK309337 BC128132 BC128133 AAI28134 BG169612 DA461055 JF810892 AEP43759 XM_011532316 XP_011530618 XM_011532317 XP_011530619 NM_198179 NP_937822 |
| Function | Receptor for the orexigenic neuropeptide QRFP. The activity of this receptor is mediated by G proteins that modulate adenylate cyclase activity and intracellular calcium levels. {ECO:0000269|PubMed:12960173}. |
| Subcellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Specificity | Expressed widely in the brain with high levels in the hypothalamus, trigeminal ganglia and vestibular neurons, and moderate levels in the amygdala, cortex, pituitary, hippocampus, thalamus, caudate nucleus and medulla oblongata. In peripheral tissues, expressed at high levels in the retina and at moderate levels in the heart, kidney, testis and thyroid. {ECO:0000269|PubMed:11574155, ECO:0000269|PubMed:12714592}. |
Human GPR103 (NP_937822) VersaClone cDNA - RDC0377 from R&D Systems
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Mouse GPR103 (NP_937835) VersaClone cDNA - RDC0906 from R&D Systems
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Human QRFPR ORF Clone (BC128133) - CDCS419341 from Creative biogene
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