Gene Symbol | QRFPR |
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Entrez Gene | 84109 |
Alt Symbol | AQ27, GPR103, SP9155 |
Species | Human |
Gene Type | protein-coding |
Description | pyroglutamylated RFamide peptide receptor |
Other Description | G protein-coupled receptor 103|G-protein coupled receptor 103|QRFP receptor|orexigenic neuropeptide QRFP receptor|peptide P518 receptor |
Swissprots | Q96P65 |
Accessions | EAX05261 EAX05262 Q96P65 AB109629 BAC98938 AK309337 BC128132 BC128133 AAI28134 BG169612 DA461055 JF810892 AEP43759 XM_011532316 XP_011530618 XM_011532317 XP_011530619 NM_198179 NP_937822 |
Function | Receptor for the orexigenic neuropeptide QRFP. The activity of this receptor is mediated by G proteins that modulate adenylate cyclase activity and intracellular calcium levels. {ECO:0000269|PubMed:12960173}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed widely in the brain with high levels in the hypothalamus, trigeminal ganglia and vestibular neurons, and moderate levels in the amygdala, cortex, pituitary, hippocampus, thalamus, caudate nucleus and medulla oblongata. In peripheral tissues, expressed at high levels in the retina and at moderate levels in the heart, kidney, testis and thyroid. {ECO:0000269|PubMed:11574155, ECO:0000269|PubMed:12714592}. |
GPR103 CRISPR/Cas9 KO Plasmid (h) - sc-408295 from Santa Cruz Biotechnology
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GPR103 HDR Plasmid (h) - sc-408295-HDR from Santa Cruz Biotechnology
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GPR103 Double Nickase Plasmid (h) - sc-408295-NIC from Santa Cruz Biotechnology
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GPR103 Double Nickase Plasmid (h2) - sc-408295-NIC-2 from Santa Cruz Biotechnology
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GPR103 CRISPR Activation Plasmid (h) - sc-408295-ACT from Santa Cruz Biotechnology
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GPR103 CRISPR Activation Plasmid (h2) - sc-408295-ACT-2 from Santa Cruz Biotechnology
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GPR103 Lentiviral Activation Particles (h) - sc-408295-LAC from Santa Cruz Biotechnology
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GPR103 Lentiviral Activation Particles (h2) - sc-408295-LAC-2 from Santa Cruz Biotechnology
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GPR103 siRNA (h) - sc-60729 from Santa Cruz Biotechnology
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GPR103 shRNA Plasmid (h) - sc-60729-SH from Santa Cruz Biotechnology
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GPR103 shRNA (h) Lentiviral Particles - sc-60729-V from Santa Cruz Biotechnology
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GPR103 RNAi - H00084109-R02 from Novus Biologicals
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MISSION® esiRNA - EHU022501 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17788 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17788 from Sigma-Aldrich
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QRFPR siRNA (Human) - CRJ3306 from Cohesion Biosciences
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QRFPR - MBS8208392 from MyBioSource
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shRNA set against Human QRFPR (NM_198179.2) - SHH387640 from Creative biogene
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shRNA set against Human GPR103(NM_198179.2) - SHH096941 from Creative biogene
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Human QRFPR siRNA - orb273807 from Biorbyt
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QRFPR shRNA Plasmid (Human) - CHJ3306 from Cohesion Biosciences
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QRFPR miRNA 3'UTR clone - MiUTR1H-04173 from Creative biogene
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