Gene Symbol | UGT2B17 |
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Entrez Gene | 7367 |
Alt Symbol | BMND12, UDPGT2B17 |
Species | Human |
Gene Type | protein-coding |
Description | UDP glucuronosyltransferase 2 family, polypeptide B17 |
Other Description | C19-steroid-specific UDP-glucuronosyltransferase|C19-steroid-specific UDPGT|UDP glycosyltransferase 2 family, member B17|UDP-glucuronosyltransferase 2B17|UDP-glucuronyltransferase, family 2, beta-17 |
Swissprots | O75795 |
Accessions | EAW55622 O75795 BC141517 AAI41518 U59209 AAC25491 NM_001077 NP_001068 |
Function | UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. The major substrates of this isozyme are eugenol > 4-methylumbelliferone > dihydrotestosterone (DHT) > androstane-3-alpha,17-beta-diol (3-alpha-diol) > testosterone > androsterone (ADT). |
Subcellular Location | Microsome membrane {ECO:0000305}; Single- pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Expressed in various tissues including the liver, kidney, testis, uterus, placenta, mammary gland, adrenal gland, skin and prostate. |
Top Pathways | Chemical carcinogenesis, Steroid hormone biosynthesis, Drug metabolism - other enzymes, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450 |
Anti-UGT2B17 antibody - ab92610 from Abcam
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ANTI-UDB17 (CENTER) antibody produced in rabbit - SAB1301563 from Sigma-Aldrich
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UGT2B17 Antibody - middle region (OAAB03489) - OAAB03489 from Aviva Systems Biology
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UDB17-Antibody-Center - AP6505c from Abgent, a WuXi AppTec company
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UGT2B17 (Center) antibody - AP17820PU-N from Acris Antibodies
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UGT2B17 antibody - H00007367-B01P from Acris Antibodies
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Rabbit Anti-Human UDB17 (Center) - 102-16787 from RayBiotech
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UDB17 antibody (Center) - STJ49984 from St John's Laboratory Ltd
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Anti-UGT2B17 monoclonal antibody - DCABH-13920 from Creative Diagnostics
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UGT2B17 Polyclonal Antibody - PA5-13430 from Thermo Fisher Scientific
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UDB17, Polyclonal Antibody - MBS9213607 from MyBioSource
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Anti-UGT2B17 (internal region) polyclonal antibody - CABT-BL5948 from Creative Diagnostics
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UGT2B Antibody - DF7734 from Affinity Biosciences
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Anti-UGT2B17 Antibody A04763 - A04763 from Boster Bio
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UGT2B Antibody - 45123 from Signalway Antibody
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UDB17 Antibody - 62-285 from ProSci
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UGT2B17 Antibody - middle region (ARP76685_P050) - ARP76685_P050 from Aviva Systems Biology
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UGT2B17 antibody - orb55759 from Biorbyt
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