YME1L1

Gene Symbol YME1L1
Entrez Gene 10730
Alt Symbol FTSH, MEG4, PAMP, YME1L
Species Human
Gene Type protein-coding
Description YME1-like 1 ATPase
Other Description ATP-dependent metalloprotease FtsH1 homolog|ATP-dependent metalloprotease YME1L1|ATP-dependent zinc metalloprotease YME1L1|YME1-like protein 1|meg-4|presenilin-associated metalloprotease
Swissprots Q96TA2 Q9H1Q0 Q5T8D9 D3DRV8 Q9UMR9 D3DRV9 B4DNM1
Accessions CAB99462 CBF59687 CBF67033 CBU84931 CBU91906 EAW86068 EAW86069 EAW86070 EAW86071 EAW86072 Q96TA2 AF018171 AAB70570 AF070656 AAD20962 AF151782 AAK57555 AI042625 AJ132637 CAB51858 AK001259 AK022930 AK291292 BAF83981 AK297973 BAG60283 AK309708 AK314372 AY358484 AAQ88848 BC007795 AAH07795 BC019602 AAH19602 BC023507 AAH23507 BC024032 AAH24032 DA395557 DA489399 XM_011519300 XP_011517602 NM_001253866 NP_001240795 NM_014263 NP_055078 NM_139312 NP_647473 NM_139313
Function Putative ATP-dependent protease which plays a role in mitochondrial protein metabolism. Ensures cell proliferation, maintains normal cristae morphology and complex I respiration activity, promotes antiapoptotic activity and protects mitochondria from the accumulation of oxidatively damaged membrane proteins. Requires to control the accumulation of nonassembled respiratory chain subunits (NDUFB6, OX4 and ND1). Seems to act in the processing of OPA1. {ECO:0000269|PubMed:18076378, ECO:0000269|PubMed:22262461}.
Subcellular Location Mitochondrion inner membrane {ECO:0000269|PubMed:10843804, ECO:0000269|PubMed:22262461}.
Tissue Specificity High expression in cardiac and skeletal muscle mitochondria. {ECO:0000269|PubMed:22262461}.

YME1L1 CRISPR/Cas9 KO Plasmid (h) - sc-409793 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

YME1L1 HDR Plasmid (h) - sc-409793-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

YME1L1 Double Nickase Plasmid (h) - sc-409793-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

YME1L1 Double Nickase Plasmid (h2) - sc-409793-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

YME1L1 CRISPR Activation Plasmid (h) - sc-409793-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

YME1L1 CRISPR Activation Plasmid (h2) - sc-409793-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

YME1L1 Lentiviral Activation Particles (h) - sc-409793-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

YME1L1 Lentiviral Activation Particles (h2) - sc-409793-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

YME1L1 siRNA (h) - sc-90696 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

YME1L1 shRNA Plasmid (h) - sc-90696-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

YME1L1 shRNA (h) Lentiviral Particles - sc-90696-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

YME1L1 RNAi - H00010730-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

YME1L1 RNAi - H00010730-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

YME1L1 RNAi - H00010730-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU115921 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN23016 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23016 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

YME1L1 siRNA (Human) - CRH7310 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

YME1L1 - MBS8203493 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human YME1L1 siRNA - orb267812 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

YME1L1 shRNA Plasmid (Human) - CHH7310 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

YME1L1 miRNA 3'UTR clone - MiUTR3H-09251 from Creative biogene

Species Reactivities Human

YME1L1 miRNA 3'UTR clone - MiUTR3H-09252 from Creative biogene

Species Reactivities Human
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