GHRL

Gene Symbol GHRL
Entrez Gene 51738
Alt Symbol MTLRP
Species Human
Gene Type protein-coding
Description ghrelin/obestatin prepropeptide
Other Description appetite-regulating hormone|ghrelin, growth hormone secretagogue receptor ligand|ghrelin/obestatin preprohormone|growth hormone-releasing peptide|motilin-related peptide|prepro-appetite regulatory hormone
Swissprots Q86YP8 A8DN30 Q9UBU3 Q9H3R3 A8CF42 Q8TAT9 A8CF34 A8CF38 A8DN29
Accessions AAG10300 AAU93610 ABN09830 ABN09831 ABN09832 ABN09833 CBI12214 CBI12216 EAW64074 EAW64075 EAW64076 Q9UBU3 AB029434 BAA89371 AB035700 BAB19045 AJ252278 CAB65733 AY184207 AAO27351 AY359053 AAQ89412 BC025791 AAH25791 BM854032 DQ891018 ABM81944 DQ894198 ABM85124 EF139854 EF139855 EF139856 EF139857 EF549557 ABQ40356 EF549561 EF549562 EF549563 EF549564 EF549565 EF549566 EF549567 EF549569 ABQ40357 EF549571 ABQ40358 EF549572 ABQ40359 EF549573 ABQ40360 EF549574 ABQ40361 EF549575 ABQ40362 EU072083 ABV55186 EU072084 ABV55187 EU072085 ABV55188 EU072086 ABV55189 EU072087 ABV55190 GU942497 ADM33790 JN243773 AEP25453 NM_001134941 NP_001128413 NM_001134944 NP_001128416 NM_001134945 NP_001128417 NM_001134946 NP_001128418 NM_001302821 NP_001289750 NM_001302822 NP_001289751 NM_001302823 NP_001289752 NM_001302824 NP_001289753 NM_001302825 NP_001289754 NM_016362 NP_057446 NR_126505
Function Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.
Subcellular Location Secreted.
Tissue Specificity Highest level in stomach. All forms are found in serum as well. Other tissues compensate for the loss of ghrelin synthesis in the stomach following gastrectomy. {ECO:0000269|PubMed:12414809}.
Top Pathways cAMP signaling pathway

ghrelin (C-18) - sc-10368 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ghrelin (C-18): sc-10368. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

ghrelin (H-40) - sc-50297 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ghrelin (H-40): sc-50297. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

Anti-Ghrelin antibody - ab57222 from Abcam

Prices $385.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Ghrelin antibody (ab57222) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human stomach.

Anti-Ghrelin antibody - ab104307 from Abcam

Prices $376.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Formalin-fixed, paraffin-embedded Human Colon stained with ab104307 at 2 ug/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-Ghrelin antibody - ab64325 from Abcam

Prices $372.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Ghrelin antibody - ab19314 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Ghrelin antibody [2F4] - ab189162 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2F4
Immunohistochemical analysis of formalin/PFA-fixed paraffin-embedded Human colon sections (epithelium) labeling Obestatin ab189162 at 5 µg/ml.

Anti-Ghrelin antibody [45] - ab112477 from Abcam

Prices $369.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 45

Anti-Ghrelin antibody [4B8] - ab117620 from Abcam

Prices $384.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 4B8
Anti-Ghrelin antibody [4B8] (ab117620) at 1/500 dilution + HeLa cell lysate

Anti-Obestatin antibody - ab41704 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC - Wholemount of sheep duodenum tissue labelling Obestatin with ab41704. Sample was incubated with primary antibody (1/400) at 4°C. ab6795, a HRP-conjugated sheep anti-rabbit polyclonal (1/800) was used as the secondary antibody.See Abreview

Anti-GHRL / Ghrelin Preproprotein Antibody (aa103-117) IHC-plus™ - LS-B3009 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-Ghrelin antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3009 concentration 2 ug/ml.

Anti-Ghrelin Antibody - LS-C15328 from LifeSpan Bioscience

Prices $650.00
Sizes 1 mg
Host Mouse
Clonality Monoclonal

Anti-Ghrelin Antibody (clone Ghr6) - LS-C15330 from LifeSpan Bioscience

Prices $650.00
Sizes 500 µg
Host Mouse
Clonality Monoclonal
Clone Ghr6

Anti-Ghrelin Antibody - LS-C15329 from LifeSpan Bioscience

Prices $335.00
Sizes 250 µg
Host Mouse
Clonality Monoclonal

Anti-Ghrelin Antibody (Octanoyl-Ser3) - LS-C15334 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-Ghrelin Antibody - LS-C15333 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-Ghrelin Antibody (aa24-37) - LS-C32629 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µl
Host Chicken
Clonality Polyclonal

Anti-Ghrelin Antibody - LS-C36430 from LifeSpan Bioscience

Prices $415.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-Ghrelin Antibody (C-Terminus) - LS-C48968 from LifeSpan Bioscience

Prices $410.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Ghrelin Antibody (C-Terminus) - LS-C48967 from LifeSpan Bioscience

Prices $410.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Ghrelin Antibody (clone GHR6) - LS-C52090 from LifeSpan Bioscience

Prices $485.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone GHR6

Anti-Ghrelin Antibody (clone GHR5) - LS-C52089 from LifeSpan Bioscience

Prices $485.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone GHR5

Anti-Ghrelin Antibody (clone GHR2) - LS-C52091 from LifeSpan Bioscience

Prices $485.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone GHR2

Anti-Ghrelin Antibody - LS-C66505 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-Ghrelin Antibody - LS-C66506 from LifeSpan Bioscience

Prices $485.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
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