GHRL

Gene Symbol GHRL
Entrez Gene 51738
Alt Symbol MTLRP
Species Human
Gene Type protein-coding
Description ghrelin/obestatin prepropeptide
Other Description appetite-regulating hormone|ghrelin, growth hormone secretagogue receptor ligand|ghrelin/obestatin preprohormone|growth hormone-releasing peptide|motilin-related peptide|prepro-appetite regulatory hormone
Swissprots Q86YP8 A8DN30 Q9UBU3 Q9H3R3 A8CF42 Q8TAT9 A8CF34 A8CF38 A8DN29
Accessions AAG10300 AAU93610 ABN09830 ABN09831 ABN09832 ABN09833 CBI12214 CBI12216 EAW64074 EAW64075 EAW64076 Q9UBU3 AB029434 BAA89371 AB035700 BAB19045 AJ252278 CAB65733 AY184207 AAO27351 AY359053 AAQ89412 BC025791 AAH25791 BM854032 DQ891018 ABM81944 DQ894198 ABM85124 EF139854 EF139855 EF139856 EF139857 EF549557 ABQ40356 EF549561 EF549562 EF549563 EF549564 EF549565 EF549566 EF549567 EF549569 ABQ40357 EF549571 ABQ40358 EF549572 ABQ40359 EF549573 ABQ40360 EF549574 ABQ40361 EF549575 ABQ40362 EU072083 ABV55186 EU072084 ABV55187 EU072085 ABV55188 EU072086 ABV55189 EU072087 ABV55190 GU942497 ADM33790 JN243773 AEP25453 NM_001134941 NP_001128413 NM_001134944 NP_001128416 NM_001134945 NP_001128417 NM_001134946 NP_001128418 NM_001302821 NP_001289750 NM_001302822 NP_001289751 NM_001302823 NP_001289752 NM_001302824 NP_001289753 NM_001302825 NP_001289754 NM_016362 NP_057446 NR_126505
Function Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.
Subcellular Location Secreted.
Tissue Specificity Highest level in stomach. All forms are found in serum as well. Other tissues compensate for the loss of ghrelin synthesis in the stomach following gastrectomy. {ECO:0000269|PubMed:12414809}.
Top Pathways cAMP signaling pathway

ghrelin CRISPR/Cas9 KO Plasmid (h) - sc-400794 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ghrelin HDR Plasmid (h) - sc-400794-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ghrelin Double Nickase Plasmid (h) - sc-400794-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ghrelin Double Nickase Plasmid (h2) - sc-400794-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ghrelin CRISPR Activation Plasmid (h) - sc-400794-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ghrelin CRISPR Activation Plasmid (h2) - sc-400794-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ghrelin Lentiviral Activation Particles (h) - sc-400794-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ghrelin Lentiviral Activation Particles (h2) - sc-400794-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ghrelin siRNA (h) - sc-39517 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ghrelin shRNA Plasmid (h) - sc-39517-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ghrelin shRNA (h) Lentiviral Particles - sc-39517-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN9278 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9278 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

GHRL siRNA (Human) - CRH9926 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Ghrelin/Obestatin RNAi - H00051738-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

GHRL - MBS8211182 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GHRL (NM_016362.3) - SHH300990 from Creative biogene

Category siRNA
Species Reactivities Human

Human GHRL siRNA - orb270428 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GHRL shRNA Plasmid (Human) - CHH9926 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GHRL miRNA 3'UTR clone - MiUTR4H-TG03803 from Creative biogene

Species Reactivities Human
Search more